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suck abstract from ncbi


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pmid25860404      BMJ+Clin+Evid 2015 ; 2015 (ä): ä
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  • Dengue haemorrhagic fever or dengue shock syndrome in children #MMPMID25860404
  • Alejandria MM
  • BMJ Clin Evid 2015[]; 2015 (ä): ä PMID25860404show ga
  • Introduction: Dengue haemorrhagic fever and dengue shock syndrome are major causes of hospital admission and mortality in children. Methods and outcomes: We conducted a systematic review and aimed to answer the following clinical question: What are the effects of supportive treatments for dengue haemorrhagic fever or dengue shock syndrome in children? We searched: Medline, Embase, The Cochrane Library, and other important databases up to March 2014 (BMJ Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). Results: We found nine studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions. Conclusions: In this systematic review we present information relating to the effectiveness and safety of the following interventions: adding blood component transfusion to standard intravenous fluids; adding corticosteroids or intravenous immunoglobulin to standard intravenous fluids; and crystalloids versus colloids.
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