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10.1161/JAHA.114.001754 http://scihub22266oqcxt.onion/10.1161/JAHA.114.001754 C4392449!4392449!25809548     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Am+Heart+Assoc 2015 ; 4 (3): ä Nephropedia Template TP {{tp|p=25809548|t=2015. Sequential Hybrid Procedure for Persistent Atrial Fibrillation |pdf=|usr=}}{{25809548}} gab.com Text Sequential Hybrid Procedure for Persistent Atrial Fibrillation JO: J Am Heart Assoc http://www.kidney.de/pget.php?&tw=1&pmid=25809548 #FOAvip Background: Catheter ablation of persistent atrial fibrillation yields an unsatisfactorily high number of failures. The hybrid approach has recently emerged as a technique that overcomes the limitations of both surgical and catheter procedures alone. Methods and Results: We investigated the sequential (staged) hybrid method, which consists of a surgical thoracoscopic radiofrequency ablation procedure followed by radiofrequency catheter ablation 6 to 8 weeks later using the CARTO 3 mapping system. Fifty consecutive patients (mean age 62±7 years, 32 males) with long?standing persistent atrial fibrillation (41±34 months) and a dilated left atrium (>45 mm) were included and prospectively followed in an unblinded registry. During the electrophysiological part of the study, all 4 pulmonary veins were found to be isolated in 36 (72%) patients and a complete box?lesion was confirmed in 14 (28%) patients. All gaps were successfully re?ablated. Twelve months after the completed hybrid ablation, 47 patients (94%) were in normal sinus rhythm (4 patients with paroxysmal atrial fibrillation required propafenone and 1 patient underwent a redo catheter procedure). The majority of arrhythmias recurred during the first 3 months. Beyond 12 months, there were no arrhythmia recurrences detected. The surgical part of the procedure was complicated by 7 (13.7%) major complications, while no serious adverse events were recorded during the radiofrequency catheter part of the procedure. Conclusions: The staged hybrid epicardial?endocardial treatment of long?standing persistent atrial fibrillation seems to be extremely effective in maintenance of normal sinus rhythm compared to radiofrequency catheter or surgical ablation alone. Epicardial ablation alone cannot guarantee durable transmural lesions. Clinical Trial Registration: URL: www.ablace.cz Unique identifier: cz?060520121617 Twit Text FOAVip Sequential Hybrid Procedure for Persistent Atrial Fibrillation ????J Am Heart Assoc http://www.kidney.de/pget.php?&tw=1&pmid=25809548 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25809548 #FOAvip English Wikipedia <ref>{{Cite pmid|25809548}}</ref> Sequential Hybrid Procedure for Persistent Atrial Fibrillation #MMPMID25809548 Bulava A; Mokracek A; Hanis J; Kurfirst V; Eisenberger M; Pesl L J Am Heart Assoc 2015[Mar]; 4 (3): ä PMID25809548show ga Background: Catheter ablation of persistent atrial fibrillation yields an unsatisfactorily high number of failures. The hybrid approach has recently emerged as a technique that overcomes the limitations of both surgical and catheter procedures alone. Methods and Results: We investigated the sequential (staged) hybrid method, which consists of a surgical thoracoscopic radiofrequency ablation procedure followed by radiofrequency catheter ablation 6 to 8 weeks later using the CARTO 3 mapping system. Fifty consecutive patients (mean age 62±7 years, 32 males) with long?standing persistent atrial fibrillation (41±34 months) and a dilated left atrium (>45 mm) were included and prospectively followed in an unblinded registry. During the electrophysiological part of the study, all 4 pulmonary veins were found to be isolated in 36 (72%) patients and a complete box?lesion was confirmed in 14 (28%) patients. All gaps were successfully re?ablated. Twelve months after the completed hybrid ablation, 47 patients (94%) were in normal sinus rhythm (4 patients with paroxysmal atrial fibrillation required propafenone and 1 patient underwent a redo catheter procedure). The majority of arrhythmias recurred during the first 3 months. Beyond 12 months, there were no arrhythmia recurrences detected. The surgical part of the procedure was complicated by 7 (13.7%) major complications, while no serious adverse events were recorded during the radiofrequency catheter part of the procedure. Conclusions: The staged hybrid epicardial?endocardial treatment of long?standing persistent atrial fibrillation seems to be extremely effective in maintenance of normal sinus rhythm compared to radiofrequency catheter or surgical ablation alone. Epicardial ablation alone cannot guarantee durable transmural lesions. Clinical Trial Registration: URL: www.ablace.cz Unique identifier: cz?060520121617 äSequential Hybrid Procedure for Persistent Atrial Fibrillation (epmc).pdf DeepDyve Pubget Overpricing