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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Saudi+Heart+Assoc
2015 ; 27
(2
): 71-8
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Noncompaction cardiomyopathy: A new mechanism for mitral regurgitation with
distinct clinical, echocardiographic features and pathological correlations
#MMPMID25870499
Ali SK
; Abu-Sulaiman R
; Agouba RB
J Saudi Heart Assoc
2015[Apr]; 27
(2
): 71-8
PMID25870499
show ga
Noncompaction cardiomyopathy (NCCM) is a primary, genetic cardiomyopathy with
variable clinical manifestations that include mitral regurgitation (MR). METHODS:
This study comprised patients diagnosed with NCCM and MR in two cardiac centers
(King Abdul-Aziz Cardiac Center, Riyadh, Kingdom of Saudi Arabia and Sudan Heart
Institute, Khartoum, Sudan), and seen in the period between 2002 and 2013. The
study describes follow up, clinical, echocardiographic, and histopathological
findings. RESULTS: Nineteen cases (85% females) were identified. Ten percent of
the cases had relapses and remissions of heart failure. Echocardiographic
features included leaflet retraction in all patients, characteristic
malcoaptation, and a zigzag deformity of anterior leaflet in 57% of patients.
Ruptured chordae were found in 15% of the patients. One patient had pathological
examination of the mitral valve which showed myxomatous degeneration, and
sclerotic and calcific changes. CONCLUSION: We describe and discuss a new
mechanism for MR caused by NCCM with identifiable clinical and echocardiographic
features, and pathological correlations.