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10.1155/2015/304208 http://scihub22266oqcxt.onion/10.1155/2015/304208 C4391155!4391155!25883951     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biomed+Res+Int 2015 ; 2015 (ä): ä Nephropedia Template TP {{tp|p=25883951|t=2015. PVT1: A Rising Star among Oncogenic Long Noncoding RNAs |pdf=|usr=}}{{25883951}} gab.com Text PVT1: A Rising Star among Oncogenic Long Noncoding RNAs JO: Biomed Res Int http://www.kidney.de/pget.php?&tw=1&pmid=25883951 #FOAvip It is becoming increasingly clear that short and long noncoding RNAs critically participate in the regulation of cell growth, differentiation, and (mis)function. However, while the functional characterization of short non-coding RNAs has been reaching maturity, there is still a paucity of well characterized long noncoding RNAs, even though large studies in recent years are rapidly increasing the number of annotated ones. The long noncoding RNA PVT1 is encoded by a gene that has been long known since it resides in the well-known cancer risk region 8q24. However, a couple of accidental concurrent conditions have slowed down the study of this gene, that is, a preconception on the primacy of the protein-coding over noncoding RNAs and the prevalent interest in its neighbor MYC oncogene. Recent studies have brought PVT1 under the spotlight suggesting interesting models of functioning, such as competing endogenous RNA activity and regulation of protein stability of important oncogenes, primarily of the MYC oncogene. Despite some advancements in modelling the PVT1 role in cancer, there are many questions that remain unanswered concerning the precise molecular mechanisms underlying its functioning. Twit Text FOAVip PVT1: A Rising Star among Oncogenic Long Noncoding RNAs ????Biomed Res Int http://www.kidney.de/pget.php?&tw=1&pmid=25883951 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25883951 #FOAvip English Wikipedia <ref>{{Cite pmid|25883951}}</ref> PVT1: A Rising Star among Oncogenic Long Noncoding RNAs #MMPMID25883951 Colombo T; Farina L; Macino G; Paci P Biomed Res Int 2015[]; 2015 (ä): ä PMID25883951show ga It is becoming increasingly clear that short and long noncoding RNAs critically participate in the regulation of cell growth, differentiation, and (mis)function. However, while the functional characterization of short non-coding RNAs has been reaching maturity, there is still a paucity of well characterized long noncoding RNAs, even though large studies in recent years are rapidly increasing the number of annotated ones. The long noncoding RNA PVT1 is encoded by a gene that has been long known since it resides in the well-known cancer risk region 8q24. However, a couple of accidental concurrent conditions have slowed down the study of this gene, that is, a preconception on the primacy of the protein-coding over noncoding RNAs and the prevalent interest in its neighbor MYC oncogene. Recent studies have brought PVT1 under the spotlight suggesting interesting models of functioning, such as competing endogenous RNA activity and regulation of protein stability of important oncogenes, primarily of the MYC oncogene. Despite some advancements in modelling the PVT1 role in cancer, there are many questions that remain unanswered concerning the precise molecular mechanisms underlying its functioning. äPVT1: A Rising Star among Oncogenic Long Noncoding RNAs (epmc).pdf DeepDyve Pubget Overpricing