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10.1016/j.clinthera.2015.02.022 http://scihub22266oqcxt.onion/10.1016/j.clinthera.2015.02.022 C4390533!4390533!25778408     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Ther 2015 ; 37 (3): 529-39 Nephropedia Template TP {{tp|p=25778408|t=2015. Not All Biofluids Are Created Equal: Chewing Over Salivary Diagnostics and the Epigenome |pdf=|usr=}}{{25778408}} gab.com Text Not All Biofluids Are Created Equal: Chewing Over Salivary Diagnostics and the Epigenome JO: Clin Ther http://www.kidney.de/pget.php?&tw=1&pmid=25778408 #FOAvip Purpose: This article describes progress to date in the characterization of the salivary epigenome and considers the importance of previous work in the salivary microbiome, proteome, endocrine analytes, genome, and transcriptome. Methods: PubMed and Web of Science were used to extensively search the existing literature (original research and reviews) related to salivary diagnostics and bio-marker development, of which 125 studies were examined. This article was derived from the most relevant 73 sources highlighting the recent state of the evolving field of salivary epigenomics and contributing significantly to the foundational work in saliva-based research. Findings: Validation of any new saliva-based diagnostic or analyte will require comparison to previously accepted standards established in blood. Careful attention to the collection, processing, and analysis of salivary analytes is critical for the development and implementation of newer applications that include genomic, transcriptomic, and epigenomic markers. All these factors must be integrated into initial study design. Implications: This commentary highlights the appeal of the salivary epigenome for translational applications and its utility in future studies of development and the interface among environment, disease, and health. Twit Text FOAVip Not All Biofluids Are Created Equal: Chewing Over Salivary Diagnostics and the Epigenome ????Clin Ther http://www.kidney.de/pget.php?&tw=1&pmid=25778408 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25778408 #FOAvip English Wikipedia <ref>{{Cite pmid|25778408}}</ref> Not All Biofluids Are Created Equal: Chewing Over Salivary Diagnostics and the Epigenome #MMPMID25778408 Wren M; Shirtcliff E; Drury SS Clin Ther 2015[Mar]; 37 (3): 529-39 PMID25778408show ga Purpose: This article describes progress to date in the characterization of the salivary epigenome and considers the importance of previous work in the salivary microbiome, proteome, endocrine analytes, genome, and transcriptome. Methods: PubMed and Web of Science were used to extensively search the existing literature (original research and reviews) related to salivary diagnostics and bio-marker development, of which 125 studies were examined. This article was derived from the most relevant 73 sources highlighting the recent state of the evolving field of salivary epigenomics and contributing significantly to the foundational work in saliva-based research. Findings: Validation of any new saliva-based diagnostic or analyte will require comparison to previously accepted standards established in blood. Careful attention to the collection, processing, and analysis of salivary analytes is critical for the development and implementation of newer applications that include genomic, transcriptomic, and epigenomic markers. All these factors must be integrated into initial study design. Implications: This commentary highlights the appeal of the salivary epigenome for translational applications and its utility in future studies of development and the interface among environment, disease, and health. äNot All Biofluids Are Created Equal: Chewing Over Salivary Diagnostics(epmc).pdf DeepDyve Pubget Overpricing