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10.1208/s12248-014-9660-1 http://scihub22266oqcxt.onion/10.1208/s12248-014-9660-1 C4389750!4389750!25193269     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       AAPS+J 2014 ; 16 (6): 1175-84 Nephropedia Template TP {{tp|p=25193269|t=2014. Next Generation Ligand Binding Assays?Review of Emerging Technologies? Capabilities to Enhance Throughput and Multiplexing |pdf=|usr=}}{{25193269}} gab.com Text Next Generation Ligand Binding Assays Review of Emerging Technologies Capabilities to Enhance Throughput and Multiplexing JO: AAPS J http://www.kidney.de/pget.php?&tw=1&pmid=25193269 #FOAvip The purpose of this manuscript is to provide a summary of the evaluation done by the Throughput and Multiplexing subteam on five emerging technologies: Single molecule array (Simoa?), Optimiser?, CyTOF® (Mass cytometry), SQIDLite?, and iLite?. Most of the information is presented with a minimum amount of published data and much is based on discussions with users and the vendor, to help provide the reader with an unbiased assessment of where the subteam sees each technology fitting best in the bioanalysis of large molecules. The evaluation focuses on technologies with advantages in throughput and multiplexing, but is wide enough to capture their strengths in other areas. While all platforms may be suited to support bioanalysis in the discovery space, because of their emergent nature, only Optimiser and SQIDLite are currently ready to be used in the regulated space. With the exception of Optimiser, each instrument/technology requires an up-front investment from the bioanalytical lab that will need justification during capital budget discussions. Ultimately, the platform choice should be driven by the quality of data, project needs, and the intended use of the data generated. In a time- and resource-constrained environment, it is not possible to evaluate all emergent technologies available in the market; we hope that this review gives the reader some of the information needed to decide which technology he/she may want to consider evaluating to support their drug development program in comparison to the options they already have in their hands. Twit Text FOAVip Next Generation Ligand Binding Assays Review of Emerging Technologies Capabilities to Enhance Throughput and Multiplexing ????AAPS J http://www.kidney.de/pget.php?&tw=1&pmid=25193269 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25193269 #FOAvip English Wikipedia <ref>{{Cite pmid|25193269}}</ref> Next Generation Ligand Binding Assays?Review of Emerging Technologies? Capabilities to Enhance Throughput and Multiplexing #MMPMID25193269 Mora J; Chunyk AG; Dysinger M; Purushothama S; Ricks C; Österlund K; Theobald V AAPS J 2014[Nov]; 16 (6): 1175-84 PMID25193269show ga The purpose of this manuscript is to provide a summary of the evaluation done by the Throughput and Multiplexing subteam on five emerging technologies: Single molecule array (Simoa?), Optimiser?, CyTOF® (Mass cytometry), SQIDLite?, and iLite?. Most of the information is presented with a minimum amount of published data and much is based on discussions with users and the vendor, to help provide the reader with an unbiased assessment of where the subteam sees each technology fitting best in the bioanalysis of large molecules. The evaluation focuses on technologies with advantages in throughput and multiplexing, but is wide enough to capture their strengths in other areas. While all platforms may be suited to support bioanalysis in the discovery space, because of their emergent nature, only Optimiser and SQIDLite are currently ready to be used in the regulated space. With the exception of Optimiser, each instrument/technology requires an up-front investment from the bioanalytical lab that will need justification during capital budget discussions. Ultimately, the platform choice should be driven by the quality of data, project needs, and the intended use of the data generated. In a time- and resource-constrained environment, it is not possible to evaluate all emergent technologies available in the market; we hope that this review gives the reader some of the information needed to decide which technology he/she may want to consider evaluating to support their drug development program in comparison to the options they already have in their hands. äNext Generation Ligand Binding Assays?Review of Emerging Technologies?(epmc).pdf DeepDyve Pubget Overpricing