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10.1371/journal.pone.0123354 http://scihub22266oqcxt.onion/10.1371/journal.pone.0123354 C4388669!4388669 !25848951     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25848951 &cmd=llinks): Failed to open stream: HTTP request failed! 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The default mode network and the working memory network are not anti-correlated during all phases of a working memory task |pdf=|usr=}}{{25848951 }} gab.com Text The default mode network and the working memory network are not anti-correlated during all phases of a working memory task JO: PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=25848951 #FOAvip INTRODUCTION: The default mode network and the working memory network are known to be anti-correlated during sustained cognitive processing, in a load-dependent manner. We hypothesized that functional connectivity among nodes of the two networks could be dynamically modulated by task phases across time. METHODS: To address the dynamic links between default mode network and the working memory network, we used a delayed visuo-spatial working memory paradigm, which allowed us to separate three different phases of working memory (encoding, maintenance, and retrieval), and analyzed the functional connectivity during each phase within and between the default mode network and the working memory network networks. RESULTS: We found that the two networks are anti-correlated only during the maintenance phase of working memory, i.e. when attention is focused on a memorized stimulus in the absence of external input. Conversely, during the encoding and retrieval phases, when the external stimulation is present, the default mode network is positively coupled with the working memory network, suggesting the existence of a dynamically switching of functional connectivity between "task-positive" and "task-negative" brain networks. CONCLUSIONS: Our results demonstrate that the well-established dichotomy of the human brain (anti-correlated networks during rest and balanced activation-deactivation during cognition) has a more nuanced organization than previously thought and engages in different patterns of correlation and anti-correlation during specific sub-phases of a cognitive task. This nuanced organization reinforces the hypothesis of a direct involvement of the default mode network in cognitive functions, as represented by a dynamic rather than static interaction with specific task-positive networks, such as the working memory network. Twit Text FOAVip The default mode network and the working memory network are not anti-correlated during all phases of a working memory task ????PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=25848951 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25848951 #FOAvip English Wikipedia <ref>{{Cite pmid|25848951 }}</ref> The default mode network and the working memory network are not anti-correlated during all phases of a working memory task #MMPMID25848951 Piccoli T ; Valente G ; Linden DE ; Re M ; Esposito F ; Sack AT ; Di Salle F PLoS One 2015[]; 10 (4 ): e0123354 PMID25848951 show ga INTRODUCTION: The default mode network and the working memory network are known to be anti-correlated during sustained cognitive processing, in a load-dependent manner. We hypothesized that functional connectivity among nodes of the two networks could be dynamically modulated by task phases across time. METHODS: To address the dynamic links between default mode network and the working memory network, we used a delayed visuo-spatial working memory paradigm, which allowed us to separate three different phases of working memory (encoding, maintenance, and retrieval), and analyzed the functional connectivity during each phase within and between the default mode network and the working memory network networks. RESULTS: We found that the two networks are anti-correlated only during the maintenance phase of working memory, i.e. when attention is focused on a memorized stimulus in the absence of external input. Conversely, during the encoding and retrieval phases, when the external stimulation is present, the default mode network is positively coupled with the working memory network, suggesting the existence of a dynamically switching of functional connectivity between "task-positive" and "task-negative" brain networks. CONCLUSIONS: Our results demonstrate that the well-established dichotomy of the human brain (anti-correlated networks during rest and balanced activation-deactivation during cognition) has a more nuanced organization than previously thought and engages in different patterns of correlation and anti-correlation during specific sub-phases of a cognitive task. This nuanced organization reinforces the hypothesis of a direct involvement of the default mode network in cognitive functions, as represented by a dynamic rather than static interaction with specific task-positive networks, such as the working memory network. |*Memory, Short-Term [MESH] |Adult [MESH] |Cerebral Cortex/physiology [MESH] |Connectome [MESH] |Female [MESH] |Humans [MESH] |Magnetic Resonance Imaging [MESH] |Male [MESH]The default mode network and the working memory network are not anti-c(epmc).pdf DeepDyve Pubget Overpricing