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10.1146/annurev-micro-092412-155725 http://scihub22266oqcxt.onion/10.1146/annurev-micro-092412-155725 C4388319!4388319 !25002086     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25002086 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Annu+Rev+Microbiol 2014 ; 68 (ä): 415-38 Nephropedia Template TP {{tp|p=25002086 |t=2014. Bacterial type III secretion systems: specialized nanomachines for protein delivery into target cells |pdf=|usr=}}{{25002086 }} gab.com Text Bacterial type III secretion systems: specialized nanomachines for protein delivery into target cells JO: Annu Rev Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=25002086 #FOAvip One of the most exciting developments in the field of bacterial pathogenesis in recent years is the discovery that many pathogens utilize complex nanomachines to deliver bacterially encoded effector proteins into target eukaryotic cells. These effector proteins modulate a variety of cellular functions for the pathogen's benefit. One of these protein-delivery machines is the type III secretion system (T3SS). T3SSs are widespread in nature and are encoded not only by bacteria pathogenic to vertebrates or plants but also by bacteria that are symbiotic to plants or insects. A central component of T3SSs is the needle complex, a supramolecular structure that mediates the passage of the secreted proteins across the bacterial envelope. Working in conjunction with several cytoplasmic components, the needle complex engages specific substrates in sequential order, moves them across the bacterial envelope, and ultimately delivers them into eukaryotic cells. The central role of T3SSs in pathogenesis makes them great targets for novel antimicrobial strategies. Twit Text FOAVip Bacterial type III secretion systems: specialized nanomachines for protein delivery into target cells ????Annu Rev Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=25002086 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25002086 #FOAvip English Wikipedia <ref>{{Cite pmid|25002086 }}</ref> Bacterial type III secretion systems: specialized nanomachines for protein delivery into target cells #MMPMID25002086 Galán JE ; Lara-Tejero M ; Marlovits TC ; Wagner S Annu Rev Microbiol 2014[]; 68 (ä): 415-38 PMID25002086 show ga One of the most exciting developments in the field of bacterial pathogenesis in recent years is the discovery that many pathogens utilize complex nanomachines to deliver bacterially encoded effector proteins into target eukaryotic cells. These effector proteins modulate a variety of cellular functions for the pathogen's benefit. One of these protein-delivery machines is the type III secretion system (T3SS). T3SSs are widespread in nature and are encoded not only by bacteria pathogenic to vertebrates or plants but also by bacteria that are symbiotic to plants or insects. A central component of T3SSs is the needle complex, a supramolecular structure that mediates the passage of the secreted proteins across the bacterial envelope. Working in conjunction with several cytoplasmic components, the needle complex engages specific substrates in sequential order, moves them across the bacterial envelope, and ultimately delivers them into eukaryotic cells. The central role of T3SSs in pathogenesis makes them great targets for novel antimicrobial strategies. |*Bacterial Secretion Systems [MESH] |Animals [MESH] |Bacteria/*chemistry/genetics/*metabolism [MESH] |Bacterial Infections/*microbiology [MESH] |Bacterial Proteins/chemistry/genetics/*metabolism [MESH] |Humans [MESH]Bacterial type III secretion systems: specialized nanomachines for pro(epmc).pdf DeepDyve Pubget Overpricing