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10.1016/j.coi.2014.01.004 http://scihub22266oqcxt.onion/10.1016/j.coi.2014.01.004 C4388310!4388310 !24531241     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24531241 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Curr+Opin+Immunol 2014 ; 27 (ä): 16-25 Nephropedia Template TP {{tp|p=24531241 |t=2014. New insights into cancer immunoediting and its three component phases--elimination, equilibrium and escape |pdf=|usr=}}{{24531241 }} gab.com Text New insights into cancer immunoediting and its three component phases--elimination, equilibrium and escape JO: Curr Opin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=24531241 #FOAvip The principles of cancer immunoediting have set the foundations for understanding the dual host-protective and tumour sculpting actions of immunity on cancer and establishing the basis for novel individualized cancer immunotherapies. During cancer immunoediting, the host immune system shapes tumour fate in three phases through the activation of innate and adaptive immune mechanisms. In the first phase, Elimination, transformed cells are destroyed by a competent immune system. Sporadic tumour cells that manage to survive immune destruction may then enter an Equilibrium phase where editing occurs. The Escape phase represents the third and final phase of the process, where immunologically sculpted tumours begin to grow progressively, become clinically apparent and establish an immunosuppressive tumour microenvironment. This review focuses on important recent developments that have enhanced our understanding of each phase of the cancer immunoediting process, summarizes the discovery of new predictive and prognostic biomarkers and discusses development of novel and objectively effective cancer immunotherapies. Twit Text FOAVip New insights into cancer immunoediting and its three component phases--elimination, equilibrium and escape ????Curr Opin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=24531241 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24531241 #FOAvip English Wikipedia <ref>{{Cite pmid|24531241 }}</ref> New insights into cancer immunoediting and its three component phases--elimination, equilibrium and escape #MMPMID24531241 Mittal D ; Gubin MM ; Schreiber RD ; Smyth MJ Curr Opin Immunol 2014[Apr]; 27 (ä): 16-25 PMID24531241 show ga The principles of cancer immunoediting have set the foundations for understanding the dual host-protective and tumour sculpting actions of immunity on cancer and establishing the basis for novel individualized cancer immunotherapies. During cancer immunoediting, the host immune system shapes tumour fate in three phases through the activation of innate and adaptive immune mechanisms. In the first phase, Elimination, transformed cells are destroyed by a competent immune system. Sporadic tumour cells that manage to survive immune destruction may then enter an Equilibrium phase where editing occurs. The Escape phase represents the third and final phase of the process, where immunologically sculpted tumours begin to grow progressively, become clinically apparent and establish an immunosuppressive tumour microenvironment. This review focuses on important recent developments that have enhanced our understanding of each phase of the cancer immunoediting process, summarizes the discovery of new predictive and prognostic biomarkers and discusses development of novel and objectively effective cancer immunotherapies. |*Tumor Escape [MESH] |Animals [MESH] |Biomarkers, Tumor/metabolism [MESH] |Disease Progression [MESH] |Humans [MESH] |Immunotherapy [MESH] |Neoplasms/*immunology/pathology/therapy [MESH]New insights into cancer immunoediting and its three component phase(epmc).pdf DeepDyve Pubget Overpricing