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10.1586/1744666X.2015.995097 http://scihub22266oqcxt.onion/10.1586/1744666X.2015.995097 C4387570!4387570!25521938     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25521938&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Expert+Rev+Clin+Immunol 2015 ; 11 (1): 155-65 Nephropedia Template TP {{tp|p=25521938|t=2015. STING, nanoparticles, autoimmune disease and cancer: a novel paradigm for immunotherapy?|pdf=|usr=}}{{25521938}} gab.com Text STING, nanoparticles, autoimmune disease and cancer: a novel paradigm for immunotherapy JO: Expert Rev Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=25521938 #FOAvip DNA has potent immunogenic properties that are useful to enhance vaccine efficacy. DNA also incites hyper-inflammation and autoimmunity if DNA sensing is not regulated. Paradoxically, DNA regulates immunity and autoimmunity when administered systemically as DNA nanoparticles (DNPs). DNPs regulated immunity via cytosolic DNA sensors that activate the signaling adaptor Stimulator of Interferon Genes (STING). In this review, we describe how DNA sensing to activate STING promotes regulatory responses and discuss the biological and clinical implications of these responses for understanding disease progression and designing better therapies for patients with chronic inflammatory diseases such as autoimmune syndromes or cancer. Twit Text FOAVip STING, nanoparticles, autoimmune disease and cancer: a novel paradigm for immunotherapy ????Expert Rev Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=25521938 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25521938 #FOAvip English Wikipedia <ref>{{Cite pmid|25521938}}</ref> STING, nanoparticles, autoimmune disease and cancer: a novel paradigm for immunotherapy? #MMPMID25521938 Lemos H; Huang L; McGaha T; Mellor AL Expert Rev Clin Immunol 2015[Jan]; 11 (1): 155-65 PMID25521938show ga DNA has potent immunogenic properties that are useful to enhance vaccine efficacy. DNA also incites hyper-inflammation and autoimmunity if DNA sensing is not regulated. Paradoxically, DNA regulates immunity and autoimmunity when administered systemically as DNA nanoparticles (DNPs). DNPs regulated immunity via cytosolic DNA sensors that activate the signaling adaptor Stimulator of Interferon Genes (STING). In this review, we describe how DNA sensing to activate STING promotes regulatory responses and discuss the biological and clinical implications of these responses for understanding disease progression and designing better therapies for patients with chronic inflammatory diseases such as autoimmune syndromes or cancer. äSTING, nanoparticles, autoimmune disease and cancer: a novel paradigm (epmc).pdf DeepDyve Pubget Overpricing