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10.1073/pnas.1417273112 http://scihub22266oqcxt.onion/10.1073/pnas.1417273112 C4386325!4386325!25775533     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2015 ; 112 (13): 4086-91 Nephropedia Template TP {{tp|p=25775533|t=2015. Atrial natriuretic peptide prevents cancer metastasis through vascular endothelial cells |pdf=|usr=}}{{25775533}} gab.com Text Atrial natriuretic peptide prevents cancer metastasis through vascular endothelial cells JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=25775533 #FOAvip Postoperative cancer recurrence is a major problem following curative cancer surgery. Perioperative systemic inflammation induces the adhesion of circulating tumor cells released from the primary tumor to the vascular endothelium of distant organs, which is the first step in hematogenous metastasis. We have previously reported that administration of atrial natriuretic peptide (ANP) during the perioperative period reduces inflammatory response and has a prophylactic effect on postoperative cardiopulmonary complications in lung cancer surgery. Here, we demonstrate that cancer recurrence after lung cancer surgery was significantly lower in ANP-treated patients than in control patients (surgery alone). We show that ANP prevents cancer metastasis by suppressing the inflammatory reaction of endothelial cells, thereby inhibiting cancer cell adhesion to vascular endothelial cells. Twit Text FOAVip Atrial natriuretic peptide prevents cancer metastasis through vascular endothelial cells ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=25775533 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25775533 #FOAvip English Wikipedia <ref>{{Cite pmid|25775533}}</ref> Atrial natriuretic peptide prevents cancer metastasis through vascular endothelial cells #MMPMID25775533 Nojiri T; Hosoda H; Tokudome T; Miura K; Ishikane S; Otani K; Kishimoto I; Shintani Y; Inoue M; Kimura T; Sawabata N; Minami M; Nakagiri T; Funaki S; Takeuchi Y; Maeda H; Kidoya H; Kiyonari H; Shioi G; Arai Y; Hasegawa T; Takakura N; Hori M; Ohno Y; Miyazato M; Mochizuki N; Okumura M; Kangawa K Proc Natl Acad Sci U S A 2015[Mar]; 112 (13): 4086-91 PMID25775533show ga Postoperative cancer recurrence is a major problem following curative cancer surgery. Perioperative systemic inflammation induces the adhesion of circulating tumor cells released from the primary tumor to the vascular endothelium of distant organs, which is the first step in hematogenous metastasis. We have previously reported that administration of atrial natriuretic peptide (ANP) during the perioperative period reduces inflammatory response and has a prophylactic effect on postoperative cardiopulmonary complications in lung cancer surgery. Here, we demonstrate that cancer recurrence after lung cancer surgery was significantly lower in ANP-treated patients than in control patients (surgery alone). We show that ANP prevents cancer metastasis by suppressing the inflammatory reaction of endothelial cells, thereby inhibiting cancer cell adhesion to vascular endothelial cells. äAtrial natriuretic peptide prevents cancer metastasis through vascular(epmc).pdf DeepDyve Pubget Overpricing