Ultrafast cone-beam computed tomography: a comparative study of imaging protocols
during image-guided therapy procedure
#MMPMID25874213
Paul J
; Chacko A
; Farhang M
; Kamali S
; Tavanania M
; Vogl T
; Panahi B
Biomed Res Int
2015[]; 2015
(?): 467850
PMID25874213
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OBJECTIVE: To evaluate two ultrafast cone-beam CT (UF-CBCT) imaging protocols
with different acquisition and injection parameters regarding image quality and
required contrast media during image-guided hepatic transarterial
chemoembolization (TACE). METHODS: In 80 patients (male: 46, female: 34; mean
age: 56.8 years; range: 33-83) UF-CBCT was performed during TACE for
intraprocedural guidance. Imaging was performed using two ultrafast CBCT
acquisition protocols with different acquisition and injection parameters
(imaging protocol 1: acquisition time 2.54?s, and contrast 6?mL with 3?s delay;
imaging protocol 2: acquisition time 2.72?s, and contrast 7?mL with 6?s delay).
Image evaluation was performed with both qualitative and quantitative methods.
Contrast injection volume and dose parameters were compared using values from the
literature. RESULTS: Imaging protocol 2 provided significantly better (P < 0.05)
image quality than protocol 1 at the cost of slightly higher contrast load and
patient dose. Imaging protocol 1 provided good contrast perfusion but it mostly
failed to delineate the tumors (P < 0.05). On the contrary, imaging protocol 2
showed excellent enhancement of hepatic parenchyma, tumor, and feeding vessels.
CONCLUSION: Tumor delineation, visualization of hepatic parenchyma, and feeding
vessels are clearly possible using imaging protocol 2 with ultrafast CBCT
imaging. A reduction of required contrast volume and patient dose were achieved
due to the ultrafast CBCT imaging.
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