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10.2174/1568009013334151 http://scihub22266oqcxt.onion/10.2174/1568009013334151 C4384701!4384701 !12188882     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=12188882 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\12188882 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Curr+Cancer+Drug+Targets 2001 ; 1 (3 ): 241-7 Nephropedia Template TP {{tp|p=12188882 |t=2001. D-RNAi (messenger RNA-antisense DNA interference) as a novel defense system against cancer and viral infections |pdf=|usr=}}{{12188882 }} gab.com Text D-RNAi (messenger RNA-antisense DNA interference) as a novel defense system against cancer and viral infections JO: Curr Cancer Drug Targets http://www.kidney.de/pget.php?&tw=1&pmid=12188882 #FOAvip D-RNAi (Messenger RNA-antisense DNA interference), a novel posttranscriptional phenomenon of silencing gene expression by transfection of mRNA-aDNA hybrids, was originally observed in the effects of bcl-2 on phorbol ester-induced apoptosis in human prostate cancer LNCaP cells. This phenomenon was also demonstrated in chicken embryos and a human CD4(+) T cell line, H9. The in vivo transduction of beta-catenin D-RNAi was shown to knock out more than 99% endogenous beta-catenin gene expression, while the in cell transfection of HIV-1 D-RNAi homolog rejected viral gene replication completely. D-RNAi was found to have long-term gene knockout effects resulting from a posttranscriptional gene silencing mechanism that may involve the homologous recombination between intracellular mRNA and the mRNA components of a D-RNAi construct. These findings provide a potential intracellular defense system against cancer and viral infections. Twit Text FOAVip D-RNAi (messenger RNA-antisense DNA interference) as a novel defense system against cancer and viral infections ????Curr Cancer Drug Targets http://www.kidney.de/pget.php?&tw=1&pmid=12188882 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=12188882 #FOAvip English Wikipedia <ref>{{Cite pmid|12188882 }}</ref> D-RNAi (messenger RNA-antisense DNA interference) as a novel defense system against cancer and viral infections #MMPMID12188882 Lin SL ; Sukasweang S ; Chuong CM ; Rasheed S ; Ying SY Curr Cancer Drug Targets 2001[Nov]; 1 (3 ): 241-7 PMID12188882 show ga D-RNAi (Messenger RNA-antisense DNA interference), a novel posttranscriptional phenomenon of silencing gene expression by transfection of mRNA-aDNA hybrids, was originally observed in the effects of bcl-2 on phorbol ester-induced apoptosis in human prostate cancer LNCaP cells. This phenomenon was also demonstrated in chicken embryos and a human CD4(+) T cell line, H9. The in vivo transduction of beta-catenin D-RNAi was shown to knock out more than 99% endogenous beta-catenin gene expression, while the in cell transfection of HIV-1 D-RNAi homolog rejected viral gene replication completely. D-RNAi was found to have long-term gene knockout effects resulting from a posttranscriptional gene silencing mechanism that may involve the homologous recombination between intracellular mRNA and the mRNA components of a D-RNAi construct. These findings provide a potential intracellular defense system against cancer and viral infections. |*Gene Silencing [MESH] |DNA, Antisense/pharmacology [MESH] |DNA, Complementary/genetics/*metabolism [MESH] |Humans [MESH] |Neoplasms/*genetics/therapy [MESH] |RNA Processing, Post-Transcriptional/genetics/physiology [MESH] |RNA, Messenger/genetics/*metabolism [MESH] |RNA, Small Interfering [MESH] |RNA, Untranslated/*genetics/*metabolism [MESH]D-RNAi (messenger RNA-antisense DNA interference) as a novel defense s(epmc).pdf DeepDyve Pubget Overpricing