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10.1155/2015/318935

http://scihub22266oqcxt.onion/10.1155/2015/318935
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C4383425!4383425!25866774
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suck abstract from ncbi


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pmid25866774      Biomed+Res+Int 2015 ; 2015 (ä): ä
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  • New Insights into Glomerular Parietal Epithelial Cell Activation and Its Signaling Pathways in Glomerular Diseases #MMPMID25866774
  • Su H; Chen S; He FF; Wang YM; Bondzie P; Zhang C
  • Biomed Res Int 2015[]; 2015 (ä): ä PMID25866774show ga
  • The glomerular parietal epithelial cells (PECs) have aroused an increasing attention recently. The proliferation of PECs is the main feature of crescentic glomerulonephritis; besides that, in the past decade, PEC activation has been identified in several types of noninflammatory glomerulonephropathies, such as focal segmental glomerulosclerosis, diabetic glomerulopathy, and membranous nephropathy. The pathogenesis of PEC activation is poorly understood; however, a few studies delicately elucidate the potential mechanisms and signaling pathways implicated in these processes. In this review we will focus on the latest observations and concepts about PEC activation in glomerular diseases and the newest identified signaling pathways in PEC activation.
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