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10.1007/s00232-015-9773-1

http://scihub22266oqcxt.onion/10.1007/s00232-015-9773-1
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C4381042!4381042!25650179
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suck abstract from ncbi


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pmid25650179      J+Membr+Biol 2015 ; 248 (2): 319-26
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  • Nd(III)-Induced Rice Mitochondrial Dysfunction Investigated by Spectroscopic and Microscopic Methods #MMPMID25650179
  • Xia CF; Lv L; Chen XY; Fu BQ; Lei KL; Qin CQ; Liu Y
  • J Membr Biol 2015[]; 248 (2): 319-26 PMID25650179show ga
  • The production capacity and yield of neodymium (Nd) in China have ranked the first in the world. Because of its unique biophysical and biochemical properties, Nd compounds have entered into the agricultural environment greatly to promote plant growth. Mitochondria play a crucial role in respiration and metabolism during the growth of plants. However, little is known about the mechanism by which Nd act at the mitochondrial level in plant cells. In this study, rice mitochondrial swelling, collapsed transmembrane potential and decreased membrane fluidity were examined to be important factors for mitochondria permeability transition pore (mPTP) opening induced by Nd(III). The protection of cyclosporin A (CsA) and dithiothreitol (DTT) could confirm that Nd(III) could trigger mPTP opening. Additionally, mitochondrial membrane breakdown observed by TEM and the release of cytochrome c (Cyt c) could also elucidate the mPTP opening from another point of view. At last, the study showed that Nd(III) could restrain the mitochondrial membrane lipid peroxide, so it might interact with anionic lipid too. This detection will be conductive to the safe application of Nd compounds in agriculture and food industry.
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