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10.1161/CIRCRESAHA.116.303630 http://scihub22266oqcxt.onion/10.1161/CIRCRESAHA.116.303630 C4380191!4380191!25814685     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Circ+Res 2015 ; 116 (7): 1245-53 Nephropedia Template TP {{tp|p=25814685|t=2015. Readers, writers and erasers: Chromatin as the Whiteboard of Heart Disease |pdf=|usr=}}{{25814685}} gab.com Text Readers, writers and erasers: Chromatin as the Whiteboard of Heart Disease JO: Circ Res http://www.kidney.de/pget.php?&tw=1&pmid=25814685 #FOAvip Dynamic packaging of DNA into strings of nucleosomes is a major mechanism whereby eukaryotic cells regulate gene expression. Intricate control of nucleosomal structure and assembly governs access of RNA polymerase II to DNA and consequent RNA synthesis. As part of this, post-translational modifications of histone proteins are central to the regulation of chromatin structure, playing vital roles in regulating the activation and repression of gene transcription. In the heart, dynamic homeostasis of histone modification ? driven by the actions of modifiers and recruitment of downstream effectors ? is a fundamental regulator of the transcriptional reprogramming that occurs in the setting of disease-related stress. Here, we examine the growing evidence for histone modification as a key mechanism governing pathological growth and remodeling of the myocardium. Twit Text FOAVip Readers, writers and erasers: Chromatin as the Whiteboard of Heart Disease ????Circ Res http://www.kidney.de/pget.php?&tw=1&pmid=25814685 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25814685 #FOAvip English Wikipedia <ref>{{Cite pmid|25814685}}</ref> Readers, writers and erasers: Chromatin as the Whiteboard of Heart Disease #MMPMID25814685 Gillette TG; Hill JA Circ Res 2015[Mar]; 116 (7): 1245-53 PMID25814685show ga Dynamic packaging of DNA into strings of nucleosomes is a major mechanism whereby eukaryotic cells regulate gene expression. Intricate control of nucleosomal structure and assembly governs access of RNA polymerase II to DNA and consequent RNA synthesis. As part of this, post-translational modifications of histone proteins are central to the regulation of chromatin structure, playing vital roles in regulating the activation and repression of gene transcription. In the heart, dynamic homeostasis of histone modification ? driven by the actions of modifiers and recruitment of downstream effectors ? is a fundamental regulator of the transcriptional reprogramming that occurs in the setting of disease-related stress. Here, we examine the growing evidence for histone modification as a key mechanism governing pathological growth and remodeling of the myocardium. äReaders, writers and erasers: Chromatin as the Whiteboard of Heart Dis(epmc).pdf DeepDyve Pubget Overpricing