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2015 ; 5
(2
): 288-99
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Strengths and limitations of tractography methods to identify the optic radiation
for epilepsy surgery
#MMPMID25853086
Lilja Y
; Nilsson DT
Quant Imaging Med Surg
2015[Apr]; 5
(2
): 288-99
PMID25853086
show ga
Diffusion tensor imaging (DTI) tractography (TG) can visualize Meyer's loop (ML),
providing important information for the epilepsy surgery team, both for
preoperative counseling and to reduce the frequency of visual field defects after
temporal lobe resection (TLR). This review highlights significant steps in the TG
process, specifically the processing of raw data including choice of TG algorithm
and the interpretation and validation of results. A lack of standardization of TG
of the optic radiation makes study comparisons challenging. We discuss results
showing differences between studies and uncertainties large enough to be of
clinical relevance and present implications of this technique for temporal lobe
epilepsy surgery. Recent studies in temporal lobe epilepsy patients, employing TG
intraoperatively, show promising results in reduction of visual field defects,
with maintained seizure reduction.