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10.1155/2015/690692 http://scihub22266oqcxt.onion/10.1155/2015/690692 C4377373!4377373!25861641     free     free     free       Biomed+Res+Int 2015 ; 2015 (ä): ä Nephropedia Template TP {{tp|p=25861641|t=2015. Factors Influencing the Eicosanoids Synthesis In Vivo |pdf=|usr=}}{{25861641}} gab.com Text Factors Influencing the Eicosanoids Synthesis In Vivo JO: Biomed Res Int http://www.kidney.de/pget.php?&tw=1&pmid=25861641 #FOAvip External factors activate a sequence of reactions involving the reception, transduction, and transmission of signals to effector cells. There are two main phases of the body's reaction to harmful factors: the first aims to neutralize the harmful factor, while in the second the inflammatory process is reduced in size and resolved. Secondary messengers such as eicosanoids are active in both phases. The discovery of lipoxins and epi-lipoxins demonstrated that not all arachidonic acid (AA) derivatives have proinflammatory activity. It was also revealed that metabolites of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) such as resolvins, protectins, and maresins also take part in the resolution of inflammation. Knowledge of the above properties has stimulated several clinical trials on the influence of EPA and DHA supplementation on various diseases. However, the equivocal results of those trials prevent the formulation of guidelines on EPA and DHA supplementation. Prescription drugs are among the substances with the strongest influence on the profile and quantity of the synthesized eicosanoids. The lack of knowledge about their influence on the conversion of EPA and DHA into eicosanoids may lead to erroneous conclusions from clinical trials. Twit Text FOAVip Factors Influencing the Eicosanoids Synthesis In Vivo ????Biomed Res Int http://www.kidney.de/pget.php?&tw=1&pmid=25861641 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25861641 #FOAvip English Wikipedia <ref>{{Cite pmid|25861641}}</ref> Factors Influencing the Eicosanoids Synthesis In Vivo #MMPMID25861641 Szefel J; Kruszewski WJ; Sobczak E Biomed Res Int 2015[]; 2015 (ä): ä PMID25861641show ga External factors activate a sequence of reactions involving the reception, transduction, and transmission of signals to effector cells. There are two main phases of the body's reaction to harmful factors: the first aims to neutralize the harmful factor, while in the second the inflammatory process is reduced in size and resolved. Secondary messengers such as eicosanoids are active in both phases. The discovery of lipoxins and epi-lipoxins demonstrated that not all arachidonic acid (AA) derivatives have proinflammatory activity. It was also revealed that metabolites of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) such as resolvins, protectins, and maresins also take part in the resolution of inflammation. Knowledge of the above properties has stimulated several clinical trials on the influence of EPA and DHA supplementation on various diseases. However, the equivocal results of those trials prevent the formulation of guidelines on EPA and DHA supplementation. Prescription drugs are among the substances with the strongest influence on the profile and quantity of the synthesized eicosanoids. The lack of knowledge about their influence on the conversion of EPA and DHA into eicosanoids may lead to erroneous conclusions from clinical trials. äFactors Influencing the Eicosanoids Synthesis In Vivo (epmc).pdf DeepDyve Pubget Overpricing