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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Ann+Thorac+Med
2015 ; 10
(2
): 87-93
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Lights and shadows of non-invasive mechanical ventilation for chronic obstructive
pulmonary disease (COPD) exacerbations
#MMPMID25829958
Lopez-Campos JL
; Jara-Palomares L
; Muñoz X
; Bustamante V
; Barreiro E
Ann Thorac Med
2015[Apr]; 10
(2
): 87-93
PMID25829958
show ga
Despite the overwhelming evidence justifying the use of non-invasive ventilation
(NIV) for providing ventilatory support in chronic obstructive pulmonary disease
(COPD) exacerbations, recent studies demonstrated that its application in
real-life settings remains suboptimal. European clinical audits have shown that
1) NIV is not invariably available, 2) its availability depends on countries and
hospital sizes, and 3) numerous centers declare their inability to provide NIV to
all of the eligible patients presenting throughout the year. Even with an
established indication, the use of NIV in acute respiratory failure due to COPD
exacerbations faces important challenges. First, the location and personnel using
NIV should be carefully selected. Second, the use of NIV is not straightforward
despite the availability of technologically advanced ventilators. Third, NIV
therapy of critically ill patients requires a thorough knowledge of both
respiratory physiology and existing ventilatory devices. Accordingly, an optimal
team-training experience, the careful selection of patients, and special
attention to the selection of devices are critical for optimizing NIV outcomes.
Additionally, when applied, NIV should be closely monitored, and endotracheal
intubation should be promptly available in the case of failure. Another topic
that merits careful consideration is the use of NIV in the elderly. This patient
population is particularly fragile, with several physiological and social
characteristics requiring specific attention in relation to NIV. Several other
novel indications should also be critically examined, including the use of NIV
during fiberoptic bronchoscopy or transesophageal echocardiography, as well as in
interventional cardiology and pulmonology. The present narrative review aims to
provide updated information on the use of NIV in acute settings to improve the
clinical outcomes of patients hospitalized for COPD exacerbations.