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10.1371/journal.pone.0119156 http://scihub22266oqcxt.onion/10.1371/journal.pone.0119156 C4374947!4374947 !25811382     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25811382 &cmd=llinks): Failed to open stream: HTTP request failed! 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The spectrum of kidney pathology in B-cell chronic lymphocytic leukemia / small lymphocytic lymphoma: a 25-year multicenter experience |pdf=|usr=}}{{25811382 }} gab.com Text The spectrum of kidney pathology in B-cell chronic lymphocytic leukemia / small lymphocytic lymphoma: a 25-year multicenter experience JO: PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=25811382 #FOAvip BACKGROUND: Chronic lymphocytic leukemia and small lymphocytic lymphoma are 2 different presentations of the most common B-cell neoplasm in western countries (CLL/SLL). In this disease, kidney involvement is usually silent, and is rarely reported in the literature. This study provides a clinicopathological analysis of all-cause kidney disease in CLL/SLL patients. METHODS: Fifteen CLL/SLL patients with kidney biopsy were identified retrospectively. Demographic, clinical, pathological and laboratory data were assessed at biopsy, and during follow-up. RESULTS: At biopsy 11 patients presented impaired renal function, 7 patients nephrotic syndrome, 6 patients dysproteinemia, and 3 patients cryoglobulinemia. Kidney pathology revealed CLL/SLL-specific monoclonal infiltrate in 10 biopsies, glomerulopathy in 9 biopsies (5 membranoproliferative glomerulonephritis, 2 minimal change disease, 1 glomerulonephritis with organized microtubular monoclonal immunoglobulin deposits, 1 AHL amyloidosis). Five patients presented interstitial granulomas attributed to CLL/SLL. After treatment of the hematological disease, improvement of renal function was observed in 7/11 patients, and remission of nephrotic syndrome in 5/7 patients. During follow-up, aggravation of the kidney disease systematically occurred in the absence of favorable response to hematological treatment. CONCLUSIONS: A broad spectrum of kidney diseases is associated with CLL/SLL. In this setting, kidney biopsy can provide important information for diagnosis and therapeutic guidance. Twit Text FOAVip The spectrum of kidney pathology in B-cell chronic lymphocytic leukemia / small lymphocytic lymphoma: a 25-year multicenter experience ????PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=25811382 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25811382 #FOAvip English Wikipedia <ref>{{Cite pmid|25811382 }}</ref> The spectrum of kidney pathology in B-cell chronic lymphocytic leukemia / small lymphocytic lymphoma: a 25-year multicenter experience #MMPMID25811382 Poitou-Verkinder AL ; Francois A ; Drieux F ; Lepretre S ; Legallicier B ; Moulin B ; Godin M ; Guerrot D PLoS One 2015[]; 10 (3 ): e0119156 PMID25811382 show ga BACKGROUND: Chronic lymphocytic leukemia and small lymphocytic lymphoma are 2 different presentations of the most common B-cell neoplasm in western countries (CLL/SLL). In this disease, kidney involvement is usually silent, and is rarely reported in the literature. This study provides a clinicopathological analysis of all-cause kidney disease in CLL/SLL patients. METHODS: Fifteen CLL/SLL patients with kidney biopsy were identified retrospectively. Demographic, clinical, pathological and laboratory data were assessed at biopsy, and during follow-up. RESULTS: At biopsy 11 patients presented impaired renal function, 7 patients nephrotic syndrome, 6 patients dysproteinemia, and 3 patients cryoglobulinemia. Kidney pathology revealed CLL/SLL-specific monoclonal infiltrate in 10 biopsies, glomerulopathy in 9 biopsies (5 membranoproliferative glomerulonephritis, 2 minimal change disease, 1 glomerulonephritis with organized microtubular monoclonal immunoglobulin deposits, 1 AHL amyloidosis). Five patients presented interstitial granulomas attributed to CLL/SLL. After treatment of the hematological disease, improvement of renal function was observed in 7/11 patients, and remission of nephrotic syndrome in 5/7 patients. During follow-up, aggravation of the kidney disease systematically occurred in the absence of favorable response to hematological treatment. CONCLUSIONS: A broad spectrum of kidney diseases is associated with CLL/SLL. In this setting, kidney biopsy can provide important information for diagnosis and therapeutic guidance. |Aged [MESH] |Antineoplastic Combined Chemotherapy Protocols/therapeutic use [MESH] |Demography [MESH] |Female [MESH] |Follow-Up Studies [MESH] |Glomerulonephritis/complications [MESH] |Humans [MESH] |Kidney/diagnostic imaging/metabolism/*pathology [MESH] |Leukemia, Lymphocytic, Chronic, B-Cell/drug therapy/metabolism/*pathology [MESH] |Lymphocyte Count [MESH] |Male [MESH] |Middle Aged [MESH] |Nephrotic Syndrome/complications [MESH] |Radiography [MESH] |Recurrence [MESH]The spectrum of kidney pathology in B-cell chronic lymphocytic leukemi(epmc).pdf DeepDyve Pubget Overpricing