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2015 ; 41 Suppl 2
(Suppl 2
): S483-91
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Thinking clearly about schizotypy: hewing to the schizophrenia liability core,
considering interesting tangents, and avoiding conceptual quicksand
#MMPMID25810061
Lenzenweger MF
Schizophr Bull
2015[Mar]; 41 Suppl 2
(Suppl 2
): S483-91
PMID25810061
show ga
The concept of schizotypy represents a rich and complex psychopathology
construct. Furthermore, the construct implies a theoretical model that has
considerable utility as an organizing framework for the study of schizophrenia,
schizophrenia-related psychopathology (eg, delusional disorder, psychosis-NOS
(not otherwise specified), schizotypal, and paranoid personality disorder), and
putative schizophrenia endophenotypes as suggested by Rado, Meehl, Gottesman,
Lenzenweger, and others. The understanding (and misunderstanding) of the
schizophrenia-related schizotypy model, particularly as regards clinical illness,
as well as an alternative approach to the construct require vigilance in order to
ensure the methodological approach continues to yield the fruit that it can in
illuminating the pathogenesis of schizophrenia-related psychopathology. The
articles in the Special Section in this issue of Schizophrenia Bulletin highlight
methodological and theoretical issues that should be examined carefully.