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10.1111/j.1582-4934.2009.00987.x

http://scihub22266oqcxt.onion/10.1111/j.1582-4934.2009.00987.x
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C4373358!4373358!20015202
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suck abstract from ncbi

pmid20015202      J+Cell+Mol+Med 2011 ; 15 (8): 1645-87
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  • Growth factors in ischemic stroke #MMPMID20015202
  • Lanfranconi S; Locatelli F; Corti S; Candelise L; Comi GP; Baron PL; Strazzer S; Bresolin N; Bersano A
  • J Cell Mol Med 2011[Aug]; 15 (8): 1645-87 PMID20015202show ga
  • Data from pre-clinical and clinical studies provide evidence that colony-stimulating factors (CSFs) and other growth factors (GFs) can improve stroke outcome by reducing stroke damage through their anti-apoptotic and anti-inflammatory effects, and by promoting angiogenesis and neurogenesis. This review provides a critical and up-to-date literature review on CSF use in stroke. We searched for experimental and clinical studies on haemopoietic GFs such as granulocyte CSF, erythropoietin, granulocyte-macrophage colony-stimulating factor, stem cell factor (SCF), vascular endothelial GF, stromal cell-derived factor-1? and SCF in ischemic stroke. We also considered studies on insulin-like growth factor-1 and neurotrophins. Despite promising results from animal models, the lack of data in human beings hampers efficacy assessments of GFs on stroke outcome. We provide a comprehensive and critical view of the present knowledge about GFs and stroke, and an overview of ongoing and future prospects.
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