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Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 J+Neurol 2015 ; 262 (3): 783-8 Nephropedia Template TP
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Key emerging issues in progressive supranuclear palsy and corticobasal degeneration #MMPMID25701010
Josephs KA
J Neurol 2015[Mar]; 262 (3): 783-8 PMID25701010show ga
It has been approximately 50 years since neurologists were introduced to the entities progressive supranuclear palsy and corticobasal degeneration. Since the two seminal publications, there have been significant advancements in our understanding of these two neurodegenerative diseases, particularly the fact that both are associated with tau. Recent advances over the past 3 years that are notable to the field are discussed in this review that covers clinical diagnosis, pathological features, neuroimaging and CSF biomarkers, genetic associations and clinical trials related to progressive supranuclear palsy and corticobasal degeneration.