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10.1038/ni.3094 http://scihub22266oqcxt.onion/10.1038/ni.3094 C4372143!4372143 !25621825     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25621825 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Nat+Immunol 2015 ; 16 (3 ): 306-17 Nephropedia Template TP {{tp|p=25621825 |t=2015. Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets |pdf=|usr=}}{{25621825 }} gab.com Text Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets JO: Nat Immunol http://www.kidney.de/pget.php?&tw=1&pmid=25621825 #FOAvip The recognized diversity of innate lymphoid cells (ILCs) is rapidly expanding. Three ILC classes have emerged, ILC1, ILC2 and ILC3, with ILC1 and ILC3 including several subsets. The classification of some subsets is unclear, and it remains controversial whether natural killer (NK) cells and ILC1 cells are distinct cell types. To address these issues, we analyzed gene expression in ILCs and NK cells from mouse small intestine, spleen and liver, as part of the Immunological Genome Project. The results showed unique gene-expression patterns for some ILCs and overlapping patterns for ILC1 cells and NK cells, whereas other ILC subsets remained indistinguishable. We identified a transcriptional program shared by small intestine ILCs and a core ILC signature. We revealed and discuss transcripts that suggest previously unknown functions and developmental paths for ILCs. Twit Text FOAVip Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets ????Nat Immunol http://www.kidney.de/pget.php?&tw=1&pmid=25621825 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25621825 #FOAvip English Wikipedia <ref>{{Cite pmid|25621825 }}</ref> Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets #MMPMID25621825 Robinette ML ; Fuchs A ; Cortez VS ; Lee JS ; Wang Y ; Durum SK ; Gilfillan S ; Colonna M Nat Immunol 2015[Mar]; 16 (3 ): 306-17 PMID25621825 show ga The recognized diversity of innate lymphoid cells (ILCs) is rapidly expanding. Three ILC classes have emerged, ILC1, ILC2 and ILC3, with ILC1 and ILC3 including several subsets. The classification of some subsets is unclear, and it remains controversial whether natural killer (NK) cells and ILC1 cells are distinct cell types. To address these issues, we analyzed gene expression in ILCs and NK cells from mouse small intestine, spleen and liver, as part of the Immunological Genome Project. The results showed unique gene-expression patterns for some ILCs and overlapping patterns for ILC1 cells and NK cells, whereas other ILC subsets remained indistinguishable. We identified a transcriptional program shared by small intestine ILCs and a core ILC signature. We revealed and discuss transcripts that suggest previously unknown functions and developmental paths for ILCs. |Animals [MESH] |Immunity, Innate/*genetics/*immunology [MESH] |Killer Cells, Natural/immunology/physiology [MESH] |Lymphocytes/immunology/*physiology [MESH] |Male [MESH] |Mice [MESH] |Mice, Inbred C57BL [MESH]Transcriptional programs define molecular characteristics of innate ly(epmc).pdf DeepDyve Pubget Overpricing