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10.1155/2015/568543 http://scihub22266oqcxt.onion/10.1155/2015/568543 C4370199!4370199!25838639     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Mediators+Inflamm 2015 ; 2015 (ä): ä Nephropedia Template TP {{tp|p=25838639|t=2015. Pivotal Roles of GM-CSF in Autoimmunity and Inflammation |pdf=|usr=}}{{25838639}} gab.com Text Pivotal Roles of GM-CSF in Autoimmunity and Inflammation JO: Mediators Inflamm http://www.kidney.de/pget.php?&tw=1&pmid=25838639 #FOAvip Granulocyte macrophage-colony stimulating factor (GM-CSF) is a hematopoietic growth factor, which stimulates the proliferation of granulocytes and macrophages from bone marrow precursor cells. In autoimmune and inflammatory diseases, Th17 cells have been considered as strong inducers of tissue inflammation. However, recent evidence indicates that GM-CSF has prominent proinflammatory functions and that this growth factor (not IL-17) is critical for the pathogenicity of CD4+ T cells. Therefore, the mechanism of GM-CSF-producing CD4+ T cell differentiation and the role of GM-CSF in the development of autoimmune and inflammatory diseases are gaining increasing attention. This review summarizes the latest knowledge of GM-CSF and its relationship with autoimmune and inflammatory diseases. The potential therapies targeting GM-CSF as well as their possible side effects have also been addressed in this review. Twit Text FOAVip Pivotal Roles of GM-CSF in Autoimmunity and Inflammation ????Mediators Inflamm http://www.kidney.de/pget.php?&tw=1&pmid=25838639 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25838639 #FOAvip English Wikipedia <ref>{{Cite pmid|25838639}}</ref> Pivotal Roles of GM-CSF in Autoimmunity and Inflammation #MMPMID25838639 Shiomi A; Usui T Mediators Inflamm 2015[]; 2015 (ä): ä PMID25838639show ga Granulocyte macrophage-colony stimulating factor (GM-CSF) is a hematopoietic growth factor, which stimulates the proliferation of granulocytes and macrophages from bone marrow precursor cells. In autoimmune and inflammatory diseases, Th17 cells have been considered as strong inducers of tissue inflammation. However, recent evidence indicates that GM-CSF has prominent proinflammatory functions and that this growth factor (not IL-17) is critical for the pathogenicity of CD4+ T cells. Therefore, the mechanism of GM-CSF-producing CD4+ T cell differentiation and the role of GM-CSF in the development of autoimmune and inflammatory diseases are gaining increasing attention. This review summarizes the latest knowledge of GM-CSF and its relationship with autoimmune and inflammatory diseases. The potential therapies targeting GM-CSF as well as their possible side effects have also been addressed in this review. äPivotal Roles of GM-CSF in Autoimmunity and Inflammation (epmc).pdf DeepDyve Pubget Overpricing