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10.3389/fphys.2015.00061 http://scihub22266oqcxt.onion/10.3389/fphys.2015.00061 C4367171!4367171!25852563     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Physiol 2015 ; 6 (ä): ä Nephropedia Template TP {{tp|p=25852563|t=2015. The pathophysiology of intestinal lipoprotein production |pdf=|usr=}}{{25852563}} gab.com Text The pathophysiology of intestinal lipoprotein production JO: Front Physiol http://www.kidney.de/pget.php?&tw=1&pmid=25852563 #FOAvip Intestinal lipoprotein production is a multistep process, essential for the absorption of dietary fats and fat-soluble vitamins. Chylomicron assembly begins in the endoplasmic reticulum with the formation of primordial, phospholipids-rich particles that are then transported to the Golgi for secretion. Several classes of transporters play a role in the selective uptake and/or export of lipids through the villus enterocytes. Once secreted in the lymph stream, triglyceride-rich lipoproteins (TRLs) are metabolized by Lipoprotein lipase (LPL), which catalyzes the hydrolysis of triacylglycerols of very low density lipoproteins (VLDLs) and chylomicrons, thereby delivering free fatty acids to various tissues. Genetic mutations in the genes codifying for these proteins are responsible of different inherited disorders affecting chylomicron metabolism. This review focuses on the molecular pathways that modulate the uptake and the transport of lipoproteins of intestinal origin and it will highlight recent findings on TRLs assembly. Twit Text FOAVip The pathophysiology of intestinal lipoprotein production ????Front Physiol http://www.kidney.de/pget.php?&tw=1&pmid=25852563 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25852563 #FOAvip English Wikipedia <ref>{{Cite pmid|25852563}}</ref> The pathophysiology of intestinal lipoprotein production #MMPMID25852563 Giammanco A; Cefalù AB; Noto D; Averna MR Front Physiol 2015[]; 6 (ä): ä PMID25852563show ga Intestinal lipoprotein production is a multistep process, essential for the absorption of dietary fats and fat-soluble vitamins. Chylomicron assembly begins in the endoplasmic reticulum with the formation of primordial, phospholipids-rich particles that are then transported to the Golgi for secretion. Several classes of transporters play a role in the selective uptake and/or export of lipids through the villus enterocytes. Once secreted in the lymph stream, triglyceride-rich lipoproteins (TRLs) are metabolized by Lipoprotein lipase (LPL), which catalyzes the hydrolysis of triacylglycerols of very low density lipoproteins (VLDLs) and chylomicrons, thereby delivering free fatty acids to various tissues. Genetic mutations in the genes codifying for these proteins are responsible of different inherited disorders affecting chylomicron metabolism. This review focuses on the molecular pathways that modulate the uptake and the transport of lipoproteins of intestinal origin and it will highlight recent findings on TRLs assembly. äThe pathophysiology of intestinal lipoprotein production (epmc).pdf DeepDyve Pubget Overpricing