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10.15252/embj.201488645 http://scihub22266oqcxt.onion/10.15252/embj.201488645 C4365030!4365030!25603932     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       EMBO+J 2015 ; 34 (5): 593-608 Nephropedia Template TP {{tp|p=25603932|t=2015. The mRNA decay factor PAT1 functions in a pathway including MAP kinase 4 and immune receptor SUMM2 |pdf=|usr=}}{{25603932}} gab.com Text The mRNA decay factor PAT1 functions in a pathway including MAP kinase 4 and immune receptor SUMM2 JO: EMBO J http://www.kidney.de/pget.php?&tw=1&pmid=25603932 #FOAvip Multi-layered defense responses are activated in plants upon recognition of invading pathogens. Transmembrane receptors recognize conserved pathogen-associated molecular patterns (PAMPs) and activate MAP kinase cascades, which regulate changes in gene expression to produce appropriate immune responses. For example, Arabidopsis MAP kinase 4 (MPK4) regulates the expression of a subset of defense genes via at least one WRKY transcription factor. We report here that MPK4 is found in complexes in vivo with PAT1, a component of the mRNA decapping machinery. PAT1 is also phosphorylated by MPK4 and, upon flagellin PAMP treatment, PAT1 accumulates and localizes to cytoplasmic processing (P) bodies which are sites for mRNA decay. Pat1 mutants exhibit dwarfism and de-repressed immunity dependent on the immune receptor SUMM2. Since mRNA decapping is a critical step in mRNA turnover, linking MPK4 to mRNA decay via PAT1 provides another mechanism by which MPK4 may rapidly instigate immune responses. Twit Text FOAVip The mRNA decay factor PAT1 functions in a pathway including MAP kinase 4 and immune receptor SUMM2 ????EMBO J http://www.kidney.de/pget.php?&tw=1&pmid=25603932 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25603932 #FOAvip English Wikipedia <ref>{{Cite pmid|25603932}}</ref> The mRNA decay factor PAT1 functions in a pathway including MAP kinase 4 and immune receptor SUMM2 #MMPMID25603932 Roux ME; Rasmussen MW; Palma K; Lolle S; Regué ÀM; Bethke G; Glazebrook J; Zhang W; Sieburth L; Larsen MR; Mundy J; Petersen M EMBO J 2015[Mar]; 34 (5): 593-608 PMID25603932show ga Multi-layered defense responses are activated in plants upon recognition of invading pathogens. Transmembrane receptors recognize conserved pathogen-associated molecular patterns (PAMPs) and activate MAP kinase cascades, which regulate changes in gene expression to produce appropriate immune responses. For example, Arabidopsis MAP kinase 4 (MPK4) regulates the expression of a subset of defense genes via at least one WRKY transcription factor. We report here that MPK4 is found in complexes in vivo with PAT1, a component of the mRNA decapping machinery. PAT1 is also phosphorylated by MPK4 and, upon flagellin PAMP treatment, PAT1 accumulates and localizes to cytoplasmic processing (P) bodies which are sites for mRNA decay. Pat1 mutants exhibit dwarfism and de-repressed immunity dependent on the immune receptor SUMM2. Since mRNA decapping is a critical step in mRNA turnover, linking MPK4 to mRNA decay via PAT1 provides another mechanism by which MPK4 may rapidly instigate immune responses. äThe mRNA decay factor PAT1 functions in a pathway including MAP kinase(epmc).pdf DeepDyve Pubget Overpricing