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10.1172/JCI76305

http://scihub22266oqcxt.onion/10.1172/JCI76305
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C4362264!4362264!25729850
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suck abstract from ncbi


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pmid25729850      J+Clin+Invest 2015 ; 125 (3): 939-48
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  • Roux-en-Y gastric bypass: effects on feeding behavior and underlying mechanisms #MMPMID25729850
  • Manning S; Pucci A; Batterham RL
  • J Clin Invest 2015[Mar]; 125 (3): 939-48 PMID25729850show ga
  • Bariatric surgery is the most effective treatment for severe obesity, producing marked sustained weight loss with associated reduced morbidity and mortality. Roux-en-Y gastric bypass surgery (RYGBP), the most commonly performed procedure, was initially viewed as a hybrid restrictive-malabsorptive procedure. However, over the last decade, it has become apparent that alternative physiologic mechanisms underlie its beneficial effects. RYGBP-induced altered feeding behavior, including reduced appetite and changes in taste/food preferences, is now recognized as a key driver of the sustained postoperative weight loss. The brain ultimately determines feeding behavior, and here we review the mechanisms by which RYGBP may affect central appetite-regulating pathways.
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