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10.1242/dev.119685 http://scihub22266oqcxt.onion/10.1242/dev.119685 C4360178!4360178!25725068     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Development 2015 ; 142 (6): 1062-72 Nephropedia Template TP {{tp|p=25725068|t=2015. teashirt is required for head-versus-tail regeneration polarity in planarians |pdf=|usr=}}{{25725068}} gab.com Text teashirt is required for head-versus-tail regeneration polarity in planarians JO: Development http://www.kidney.de/pget.php?&tw=1&pmid=25725068 #FOAvip Regeneration requires that the identities of new cells are properly specified to replace missing tissues. The Wnt signaling pathway serves a central role in specifying posterior cell fates during planarian regeneration. We identified a gene encoding a homolog of the Teashirt family of zinc-finger proteins in the planarian Schmidtea mediterranea to be a target of Wnt signaling in intact animals and at posterior-facing wounds. Inhibition of Smed-teashirt (teashirt) by RNA interference (RNAi) resulted in the regeneration of heads in place of tails, a phenotype previously observed with RNAi of the Wnt pathway genes ?-catenin-1, wnt1, Dvl-1/2 or wntless. teashirt was required for ?-catenin-1-dependent activation of posterior genes during regeneration. These findings identify teashirt as a transcriptional target of Wnt signaling required for Wnt-mediated specification of posterior blastemas. Twit Text FOAVip teashirt is required for head-versus-tail regeneration polarity in planarians ????Development http://www.kidney.de/pget.php?&tw=1&pmid=25725068 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25725068 #FOAvip English Wikipedia <ref>{{Cite pmid|25725068}}</ref> teashirt is required for head-versus-tail regeneration polarity in planarians #MMPMID25725068 Owen JH; Wagner DE; Chen CC; Petersen CP; Reddien PW Development 2015[Mar]; 142 (6): 1062-72 PMID25725068show ga Regeneration requires that the identities of new cells are properly specified to replace missing tissues. The Wnt signaling pathway serves a central role in specifying posterior cell fates during planarian regeneration. We identified a gene encoding a homolog of the Teashirt family of zinc-finger proteins in the planarian Schmidtea mediterranea to be a target of Wnt signaling in intact animals and at posterior-facing wounds. Inhibition of Smed-teashirt (teashirt) by RNA interference (RNAi) resulted in the regeneration of heads in place of tails, a phenotype previously observed with RNAi of the Wnt pathway genes ?-catenin-1, wnt1, Dvl-1/2 or wntless. teashirt was required for ?-catenin-1-dependent activation of posterior genes during regeneration. These findings identify teashirt as a transcriptional target of Wnt signaling required for Wnt-mediated specification of posterior blastemas. äteashirt is required for head-versus-tail regeneration polarity in pla(epmc).pdf DeepDyve Pubget Overpricing