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10.1101/gad.255828.114

http://scihub22266oqcxt.onion/10.1101/gad.255828.114
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C4358405!4358405!25691092
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suck abstract from ncbi

pmid25691092      Genes+Dev 2015 ; 29 (5): 526-37
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  • Mechanism of siRNA production from repetitive DNA #MMPMID25691092
  • Yang Q; Ye QA; Liu Y
  • Genes Dev 2015[Mar]; 29 (5): 526-37 PMID25691092show ga
  • Repetitive DNA loci are a major source for the production of eukaryotic small RNAs, but how these small RNAs are produced is not clear. Yang et al. show that DNA tandem repeats and double-strand breaks are necessary and, when both are present, sufficient to trigger gene silencing and siRNA production. In addition to siRNA production, the quelling pathway also maintains tandem repeats by regulating homologous recombination.
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