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10.1074/jbc.M114.623181

http://scihub22266oqcxt.onion/10.1074/jbc.M114.623181
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C4358289!4358289!25589785
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suck abstract from ncbi


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pmid25589785      J+Biol+Chem 2015 ; 290 (10): 6558-73
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  • Distinct Requirements for HIV-Cell Fusion and HIV-mediated Cell-Cell Fusion* #MMPMID25589785
  • Kondo N; Marin M; Kim JH; Desai TM; Melikyan GB
  • J Biol Chem 2015[Mar]; 290 (10): 6558-73 PMID25589785show ga
  • Background: Determinants of HIV-1 fusion with the plasma membrane versus endosomal membrane are unknown.Results: Unlike HIV-cell fusion, HIV-mediated fusion of the plasma membranes of adjacent cells occurred with much lower probability and was actin-dependent.Conclusion: Distinct regulation of HIV-mediated cell-cell fusion and virus-cell fusion indicates that the latter events may occur in endosomes.Significance: These results shed light on the HIV entry routes.
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