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10.1074/jbc.M114.628701

http://scihub22266oqcxt.onion/10.1074/jbc.M114.628701
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C4358094!4358094!25605736
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suck abstract from ncbi


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pmid25605736      J+Biol+Chem 2015 ; 290 (11): 6705-13
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  • Quantitative Analysis of Purine Nucleotides Indicates That Purinosomes Increase de Novo Purine Biosynthesis*? #MMPMID25605736
  • Zhao H; Chiaro CR; Zhang L; Smith PB; Chan CY; Pedley AM; Pugh RJ; French JB; Patterson AD; Benkovic SJ
  • J Biol Chem 2015[Mar]; 290 (11): 6705-13 PMID25605736show ga
  • Background: Metabolic enzymes have been hypothesized to assemble into complex to respond to cellular metabolism changes.Results:De novo purine biosynthesis increases in purinosome-containing cells.Conclusion: Purine metabolism is adjusted by purinosome assembly.Significance: This study indicates that purinosome is a functional multienzyme complex.
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