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10.1128/AAC.04967-14

http://scihub22266oqcxt.onion/10.1128/AAC.04967-14
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C4356792!4356792!25624334
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suck abstract from ncbi


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pmid25624334      Antimicrob+Agents+Chemother 2015 ; 59 (4): 2446-9
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  • Eravacycline (TP-434) Is Active In Vitro against Biofilms Formed by Uropathogenic Escherichia coli #MMPMID25624334
  • Grossman TH; O'Brien W; Kerstein KO; Sutcliffe JA
  • Antimicrob Agents Chemother 2015[Apr]; 59 (4): 2446-9 PMID25624334show ga
  • Eravacycline (formerly TP-434) was evaluated in vitro against pre-established biofilms formed by a uropathogenic Escherichia coli strain. Biofilms were eradicated by 0.5 ?g/ml eravacycline, which was within 2-fold of the MIC for planktonic cells. In contrast, colistin and meropenem disrupted biofilms at 32 and 2 ?g/ml, respectively, concentrations well above their respective MICs of 0.5 and 0.03 ?g/ml. Gentamicin and levofloxacin eradicated biofilms at concentrations within 2-fold of their MICs.
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