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10.1016/j.cca.2014.10.027 http://scihub22266oqcxt.onion/10.1016/j.cca.2014.10.027 C4355214!4355214!25445413     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Chim+Acta 2015 ; 443 (ä): 3-8 Nephropedia Template TP {{tp|p=25445413|t=2015. PATHOPHYSIOLOGY AND THE CARDIORENAL CONNECTION IN HEART FAILURE CIRCULATING HORMONES: BIOMARKERS OR MEDIATORS |pdf=|usr=}}{{25445413}} gab.com Text PATHOPHYSIOLOGY AND THE CARDIORENAL CONNECTION IN HEART FAILURE CIRCULATING HORMONES: BIOMARKERS OR MEDIATORS JO: Clin Chim Acta http://www.kidney.de/pget.php?&tw=1&pmid=25445413 #FOAvip Heart failure (HF) is a syndrome characterized by a complex pathophysiology which involves multiple organ systems, with the kidney playing a major role. HF can present with reduced ejection fraction (EF), HFrEF, or with preserved EF (HFpEF). The interplay between diverse organ systems contributing to HF is mediated by the activation of counteracting neurohormonal pathways focused to re-establishing hemodynamic homeostasis. During early stages of HF, these biochemical signals, consisting mostly of hormones and neurotransmitters secreted by a variety of cell types, are compensatory and the patient is asymptomatic. However, with disease progression, the attempt to reverse or delay cardiac dysfunction is deleterious, leading to multi-organ congestion, fibrosis and decompensation and finally symptomatic HF. In conclusion, these neurohormonal pathways mediate the evolution of HF and have become a way to monitor HF. Specifically, these mediators have become important in the diagnosis and prognosis of this highly fatal cardiovascular disease. Finally, while these multiple neurohumoral factors serve as important HF biomarkers, they can also be targeted for more effective and curative HF treatments. Twit Text FOAVip PATHOPHYSIOLOGY AND THE CARDIORENAL CONNECTION IN HEART FAILURE CIRCULATING HORMONES: BIOMARKERS OR MEDIATORS ????Clin Chim Acta http://www.kidney.de/pget.php?&tw=1&pmid=25445413 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25445413 #FOAvip English Wikipedia <ref>{{Cite pmid|25445413}}</ref> PATHOPHYSIOLOGY AND THE CARDIORENAL CONNECTION IN HEART FAILURE CIRCULATING HORMONES: BIOMARKERS OR MEDIATORS #MMPMID25445413 BUGLIONI A; BURNETT JC Clin Chim Acta 2015[Mar]; 443 (ä): 3-8 PMID25445413show ga Heart failure (HF) is a syndrome characterized by a complex pathophysiology which involves multiple organ systems, with the kidney playing a major role. HF can present with reduced ejection fraction (EF), HFrEF, or with preserved EF (HFpEF). The interplay between diverse organ systems contributing to HF is mediated by the activation of counteracting neurohormonal pathways focused to re-establishing hemodynamic homeostasis. During early stages of HF, these biochemical signals, consisting mostly of hormones and neurotransmitters secreted by a variety of cell types, are compensatory and the patient is asymptomatic. However, with disease progression, the attempt to reverse or delay cardiac dysfunction is deleterious, leading to multi-organ congestion, fibrosis and decompensation and finally symptomatic HF. In conclusion, these neurohormonal pathways mediate the evolution of HF and have become a way to monitor HF. Specifically, these mediators have become important in the diagnosis and prognosis of this highly fatal cardiovascular disease. Finally, while these multiple neurohumoral factors serve as important HF biomarkers, they can also be targeted for more effective and curative HF treatments. äPATHOPHYSIOLOGY AND THE CARDIORENAL CONNECTION IN HEART FAILURE CIRCU(epmc).pdf DeepDyve Pubget Overpricing