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2015 ; 56
(2
): 129-39
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English Wikipedia
Toxicities associated with NBOMe ingestion-a novel class of potent hallucinogens:
a review of the literature
#MMPMID25659919
Suzuki J
; Dekker MA
; Valenti ES
; Arbelo Cruz FA
; Correa AM
; Poklis JL
; Poklis A
Psychosomatics
2015[Mar]; 56
(2
): 129-39
PMID25659919
show ga
BACKGROUND: A new class of synthetic hallucinogens called NBOMe has emerged as
drugs of abuse. OBJECTIVE: Our aim was to conduct a systematic review of
published reports of toxicities associated with NBOMe ingestion. METHODS: We
searched PubMed for relevant English-language citations that described adverse
effects from analytically confirmed human NBOMe ingestion. Demographic and
clinical data were extracted. RESULTS: A total of 10 citations met the criteria
for inclusion, representing 20 individual patients. 25I-NBOMe was the most common
analogue identified, followed by 25B-NBOMe and 25C-NBOMe. Fatalities were
reported in 3 (15%) cases. Of all the patients, 7 (35%) were discharged after a
period of observation, whereas 8 (40.0%) required admission to an intensive care
unit. The most common adverse effects were agitation (85.0%), tachycardia
(85.0%), and hypertension (65.0%). Seizures were reported in 8 (40.0%) patients.
The most common abnormalities reported on laboratory tests were elevated level of
creatinine kinase (45.0%), leukocytosis (25.0%), and hyperglycemia (20.0%).
CONCLUSION: NBOMe ingestion is associated with severe adverse effects. Clinicians
need to have a high index of suspicion for NBOMe ingestion in patients reporting
the recent use of hallucinogens.
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