Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.molmed.2014.11.008 http://scihub22266oqcxt.onion/10.1016/j.molmed.2014.11.008 C4352396!4352396!25500014     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Trends+Mol+Med 2015 ; 21 (3): 193-201 Nephropedia Template TP {{tp|p=25500014|t=2015. Mitochondria: Diversity in the regulation of NLRP3 inflammasome |pdf=|usr=}}{{25500014}} gab.com Text Mitochondria: Diversity in the regulation of NLRP3 inflammasome JO: Trends Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=25500014 #FOAvip Recent studies have identified new roles for mitochondria in the regulation of autoinflammatory processes. Emerging data suggests that the release of danger signals from mitochondria in response to stress and infection promotes the formation of the inflammatory signaling platform known as inflammasomes. Activation of inflammasomes by damaged mitochondria results in caspase-1-dependent secretion of the inflammatory cytokines IL-1? and IL-18, and an inflammatory form of cell death referred to as pyroptosis. Here, we review recently described mechanisms that have been proposed to be involved in mitochondria-mediated regulation of inflammasome activation and inflammation. In addition, we highlight how aberrant regulation of mitochondria-induced inflammasome activation centrally contributes to the inflammatory process that are responsible for obesity and associated metabolic diseases. Twit Text FOAVip Mitochondria: Diversity in the regulation of NLRP3 inflammasome ????Trends Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=25500014 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25500014 #FOAvip English Wikipedia <ref>{{Cite pmid|25500014}}</ref> Mitochondria: Diversity in the regulation of NLRP3 inflammasome #MMPMID25500014 Gurung P; Lukens JR; Kanneganti TD Trends Mol Med 2015[Mar]; 21 (3): 193-201 PMID25500014show ga Recent studies have identified new roles for mitochondria in the regulation of autoinflammatory processes. Emerging data suggests that the release of danger signals from mitochondria in response to stress and infection promotes the formation of the inflammatory signaling platform known as inflammasomes. Activation of inflammasomes by damaged mitochondria results in caspase-1-dependent secretion of the inflammatory cytokines IL-1? and IL-18, and an inflammatory form of cell death referred to as pyroptosis. Here, we review recently described mechanisms that have been proposed to be involved in mitochondria-mediated regulation of inflammasome activation and inflammation. In addition, we highlight how aberrant regulation of mitochondria-induced inflammasome activation centrally contributes to the inflammatory process that are responsible for obesity and associated metabolic diseases. äMitochondria: Diversity in the regulation of NLRP3 inflammasome (epmc).pdf DeepDyve Pubget Overpricing