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10.1177/1933719114557899 http://scihub22266oqcxt.onion/10.1177/1933719114557899 C4352145!4352145 !25394640     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25394640 &cmd=llinks): Failed to open stream: HTTP request failed! 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Neutrophil release of myeloperoxidase in systemic vasculature of obese women may put them at risk for preeclampsia |pdf=|usr=}}{{25394640 }} gab.com Text Neutrophil release of myeloperoxidase in systemic vasculature of obese women may put them at risk for preeclampsia JO: Reprod Sci http://www.kidney.de/pget.php?&tw=1&pmid=25394640 #FOAvip Obesity is a risk factor for preeclampsia, but the reason for this risk is unknown. Neutrophils infiltrate into systemic blood vessels of both obese and preeclamptic women. Neutrophils are a major source of myeloperoxidase (MPO), which is associated with hypertension. We tested the hypothesis that systemic vasculature of both obese and preeclamptic women will have a significant presence of MPO as a result of neutrophil infiltration. We found that immunohistochemical staining of MPO was significantly greater in subcutaneous fat blood vessels of obese women than overweight women, which was significantly greater than normal weight women. Expression of MPO was significantly greater in maternal blood vessels of preeclamptic women than normal pregnant or normal nonpregnant women. In general, when vessels of overweight or normal pregnant women were stained it was primarily for leukocytes in the lumen and not infiltrated into the vessel. In contrast, in obese and preeclamptic women staining was present for leukocytes in the lumen, flattened, and adhered to the endothelium and infiltrated into the vessel wall. There was also extensive diffuse staining for MPO in vessels of obese and preeclamptic women. In conclusion, both obese and preeclamptic women have increased presence of MPO in systemic vasculature as a result of neutrophil infiltration. We speculate that obese women may be at risk of preeclampsia because their vasculature is already prone to hypertension. Twit Text FOAVip Neutrophil release of myeloperoxidase in systemic vasculature of obese women may put them at risk for preeclampsia ????Reprod Sci http://www.kidney.de/pget.php?&tw=1&pmid=25394640 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25394640 #FOAvip English Wikipedia <ref>{{Cite pmid|25394640 }}</ref> Neutrophil release of myeloperoxidase in systemic vasculature of obese women may put them at risk for preeclampsia #MMPMID25394640 Shukla J ; Walsh SW Reprod Sci 2015[Mar]; 22 (3 ): 300-7 PMID25394640 show ga Obesity is a risk factor for preeclampsia, but the reason for this risk is unknown. Neutrophils infiltrate into systemic blood vessels of both obese and preeclamptic women. Neutrophils are a major source of myeloperoxidase (MPO), which is associated with hypertension. We tested the hypothesis that systemic vasculature of both obese and preeclamptic women will have a significant presence of MPO as a result of neutrophil infiltration. We found that immunohistochemical staining of MPO was significantly greater in subcutaneous fat blood vessels of obese women than overweight women, which was significantly greater than normal weight women. Expression of MPO was significantly greater in maternal blood vessels of preeclamptic women than normal pregnant or normal nonpregnant women. In general, when vessels of overweight or normal pregnant women were stained it was primarily for leukocytes in the lumen and not infiltrated into the vessel. In contrast, in obese and preeclamptic women staining was present for leukocytes in the lumen, flattened, and adhered to the endothelium and infiltrated into the vessel wall. There was also extensive diffuse staining for MPO in vessels of obese and preeclamptic women. In conclusion, both obese and preeclamptic women have increased presence of MPO in systemic vasculature as a result of neutrophil infiltration. We speculate that obese women may be at risk of preeclampsia because their vasculature is already prone to hypertension. |*Neutrophil Infiltration [MESH] |Adult [MESH] |Biomarkers/metabolism [MESH] |Blood Vessels/enzymology/physiopathology [MESH] |Case-Control Studies [MESH] |Female [MESH] |Humans [MESH] |Immunohistochemistry [MESH] |Neutrophils/*enzymology [MESH] |Obesity/*complications/diagnosis/enzymology [MESH] |Peroxidase/*metabolism [MESH] |Pre-Eclampsia/diagnosis/enzymology/*etiology/physiopathology [MESH] |Pregnancy [MESH] |Risk Factors [MESH] |Subcutaneous Fat/*blood supply [MESH]Neutrophil release of myeloperoxidase in systemic vasculature of obese(epmc).pdf DeepDyve Pubget Overpricing