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10.1111/iep.12075 http://scihub22266oqcxt.onion/10.1111/iep.12075 C4351859!4351859!24773279     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Exp+Pathol 2014 ; 95 (3): 229-37 Nephropedia Template TP {{tp|p=24773279|t=2014. Comparative study of Hsp27, GSK3?, Wnt1 and PRDX3 in Hirschsprung s disease |pdf=|usr=}}{{24773279}} gab.com Text Comparative study of Hsp27, GSK3 , Wnt1 and PRDX3 in Hirschsprung s disease JO: Int J Exp Pathol http://www.kidney.de/pget.php?&tw=1&pmid=24773279 #FOAvip Hirschsprung's disease (HSCR) is a developmental disorder of the enteric nervous system characterized by aganglionosis in distal gut. In this study, we used two-dimensional gel electrophoresis (2-DE) technology coupled with matrix assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) analysis to identify differentially expressed proteins in the aganglionic (stenotic) and ganglionic (normal) colon segment tissues from patients with HSCR. We identified 15 proteins with different expression levels between the stenotic and the normal colon segment tissues from patients with HSCR. Nine proteins were upregulated and six proteins downregulated in the stenotic colon segment tissues compared to the normal colon segment tissues. Based on the biological functions, we selected the Hsp27 upregulated proteins and the PRDX3 downregulated proteins to confirm their expression in 20 patients. The protein and mRNA expressions of Hsp27 were statistically higher in the stenotic colon segment tissues than in the normal colon segment tissues, whereas the protein and mRNA expressions of PRDX3 were statistically lower in the stenotic colon segment tissues than in the normal colon segment tissues. These findings of changes in mRNA and protein in tissues from patients with HSCR provide information which may be helpful in understanding the pathomechanism that is implicated in the disease. Twit Text FOAVip Comparative study of Hsp27, GSK3 , Wnt1 and PRDX3 in Hirschsprung s disease ????Int J Exp Pathol http://www.kidney.de/pget.php?&tw=1&pmid=24773279 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24773279 #FOAvip English Wikipedia <ref>{{Cite pmid|24773279}}</ref> Comparative study of Hsp27, GSK3?, Wnt1 and PRDX3 in Hirschsprung s disease #MMPMID24773279 Gao H; Liu X; Chen D; Lv L; Wu M; Mi J; Wang W Int J Exp Pathol 2014[Jun]; 95 (3): 229-37 PMID24773279show ga Hirschsprung's disease (HSCR) is a developmental disorder of the enteric nervous system characterized by aganglionosis in distal gut. In this study, we used two-dimensional gel electrophoresis (2-DE) technology coupled with matrix assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) analysis to identify differentially expressed proteins in the aganglionic (stenotic) and ganglionic (normal) colon segment tissues from patients with HSCR. We identified 15 proteins with different expression levels between the stenotic and the normal colon segment tissues from patients with HSCR. Nine proteins were upregulated and six proteins downregulated in the stenotic colon segment tissues compared to the normal colon segment tissues. Based on the biological functions, we selected the Hsp27 upregulated proteins and the PRDX3 downregulated proteins to confirm their expression in 20 patients. The protein and mRNA expressions of Hsp27 were statistically higher in the stenotic colon segment tissues than in the normal colon segment tissues, whereas the protein and mRNA expressions of PRDX3 were statistically lower in the stenotic colon segment tissues than in the normal colon segment tissues. These findings of changes in mRNA and protein in tissues from patients with HSCR provide information which may be helpful in understanding the pathomechanism that is implicated in the disease. äComparative study of Hsp27, GSK3?, Wnt1 and PRDX3 in Hirschsprung s di(epmc).pdf DeepDyve Pubget Overpricing