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10.1158/1078-0432.CCR-14-2550

http://scihub22266oqcxt.onion/10.1158/1078-0432.CCR-14-2550
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suck abstract from ncbi


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pmid25733706
      Clin+Cancer+Res 2015 ; 21 (5 ): 942-3
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  • CCR 20th anniversary commentary: Preclinical study of proteasome inhibitor bortezomib in head and neck cancer #MMPMID25733706
  • Allen CT ; Conley B ; Sunwoo JB ; Van Waes C
  • Clin Cancer Res 2015[Mar]; 21 (5 ): 942-3 PMID25733706 show ga
  • In a study published in the May 1, 2001, issue of Clinical Cancer Research, Sunwoo and colleagues provided evidence for proteasome inhibition of NF-?B and tumorigenesis, supporting early-phase clinical trials in solid malignancies of the upper aerodigestive tract. Subsequent clinical studies uncovered a dichotomy of responses in patients with hematopoietic and solid malignancies, and the mechanisms of resistance.
  • |Animals [MESH]
  • |Antineoplastic Agents/*pharmacology [MESH]
  • |Boronic Acids/*pharmacology [MESH]
  • |Humans [MESH]
  • |Multienzyme Complexes/*antagonists & inhibitors [MESH]
  • |NF-kappa B/*antagonists & inhibitors [MESH]


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