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10.1016/j.celrep.2014.07.030 http://scihub22266oqcxt.onion/10.1016/j.celrep.2014.07.030 C4350764!4350764!25176646     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Rep 2014 ; 8 (5): 1354-64 Nephropedia Template TP {{tp|p=25176646|t=2014. Adaptations to a subterranean environment and longevity revealed by the analysis of mole rat genomes |pdf=|usr=}}{{25176646}} gab.com Text Adaptations to a subterranean environment and longevity revealed by the analysis of mole rat genomes JO: Cell Rep http://www.kidney.de/pget.php?&tw=1&pmid=25176646 #FOAvip Subterranean mammals spend their lives in dark, unventilated environments rich in carbon dioxide and ammonia, and low in oxygen. Many of these animals are also long-lived and exhibit reduced aging-associated diseases, such as neurodegenerative disorders and cancer. We sequenced the genome of the Damaraland mole rat (DMR, Fukomys damarensis) and improved the genome assembly of the naked mole rat (NMR, Heterocephalus glaber). Comparative genome analysis, along with transcriptomes of related subterranean rodents, reveal candidate molecular adaptations for subterranean life and longevity, including a divergent insulin peptide, expression of oxygen-carrying globins in the brain, prevention of high CO2-induced pain perception, and enhanced ammonia detoxification. Juxtaposition of the genomes of DMR and other more conventional animals with the genome of NMR revealed several truly exceptional NMR features: unusual thermogenesis, aberrant melatonin system, pain insensitivity, and novel processing of 28S rRNA. Together, the new genomes and transcriptomes extend our understanding of subterranean adaptations, stress resistance and longevity. Twit Text FOAVip Adaptations to a subterranean environment and longevity revealed by the analysis of mole rat genomes ????Cell Rep http://www.kidney.de/pget.php?&tw=1&pmid=25176646 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25176646 #FOAvip English Wikipedia <ref>{{Cite pmid|25176646}}</ref> Adaptations to a subterranean environment and longevity revealed by the analysis of mole rat genomes #MMPMID25176646 Fang X; Seim I; Huang Z; Gerashchenko MV; Xiong Z; Turanov AA; Zhu Y; Lobanov AV; Fan D; Yim SH; Yao X; Ma S; Yang L; Lee SG; Kim EB; Bronson RT; ?umbera R; Buffenstein R; Zhou X; Krogh A; Park TJ; Zhang G; Wang J; Gladyshev VN Cell Rep 2014[Sep]; 8 (5): 1354-64 PMID25176646show ga Subterranean mammals spend their lives in dark, unventilated environments rich in carbon dioxide and ammonia, and low in oxygen. Many of these animals are also long-lived and exhibit reduced aging-associated diseases, such as neurodegenerative disorders and cancer. We sequenced the genome of the Damaraland mole rat (DMR, Fukomys damarensis) and improved the genome assembly of the naked mole rat (NMR, Heterocephalus glaber). Comparative genome analysis, along with transcriptomes of related subterranean rodents, reveal candidate molecular adaptations for subterranean life and longevity, including a divergent insulin peptide, expression of oxygen-carrying globins in the brain, prevention of high CO2-induced pain perception, and enhanced ammonia detoxification. Juxtaposition of the genomes of DMR and other more conventional animals with the genome of NMR revealed several truly exceptional NMR features: unusual thermogenesis, aberrant melatonin system, pain insensitivity, and novel processing of 28S rRNA. Together, the new genomes and transcriptomes extend our understanding of subterranean adaptations, stress resistance and longevity. äAdaptations to a subterranean environment and longevity revealed by th(epmc).pdf DeepDyve Pubget Overpricing