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10.2215/CJN.03080314 http://scihub22266oqcxt.onion/10.2215/CJN.03080314 C4348676!4348676!25568216     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+J+Am+Soc+Nephrol 2015 ; 10 (3): 382-9 Nephropedia Template TP {{tp|p=25568216|t=2015. A Systematic Review of Glomerular Hyperfiltration Assessment and Definition in the Medical Literature |pdf=|usr=}}{{25568216}} gab.com Text A Systematic Review of Glomerular Hyperfiltration Assessment and Definition in the Medical Literature JO: Clin J Am Soc Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=25568216 #FOAvip Background and objectives: Evaluation of glomerular hyperfiltration (GH) is difficult; the variable reported definitions impede comparisons between studies. A clear and universal definition of GH would help in comparing results of trials aimed at reducing GH. This study assessed how GH is measured and defined in the literature. Design, setting, participants, & measurements: Three databases (Embase, MEDLINE, CINAHL) were systematically searched using the terms ?hyperfiltration? or ?glomerular hyperfiltration?. All studies reporting a GH threshold or studying the effect of a high GFR in a continuous manner against another outcome of interest were included. Results: The literature search was performed from November 2012 to February 2013 and updated in August 2014. From 2013 retrieved studies, 405 studies were included. Threshold use to define GH was reported in 55.6% of studies. Of these, 88.4% used a single threshold and 11.6% used numerous thresholds adapted to participant sex or age. In 29.8% of the studies, the choice of a GH threshold was not based on a control group or literature references. After 2004, the use of GH threshold use increased (P<0.001), but the use of a control group to precisely define that GH threshold decreased significantly (P<0.001); the threshold did not differ among pediatric, adult, or mixed-age studies. The GH threshold ranged from 90.7 to 175 ml/min per 1.73 m2 (median, 135 ml/min per 1.73 m2). Conclusion: Thirty percent of studies did not justify the choice of threshold values. The decrease of GFR in the elderly was rarely considered in defining GH. From a methodologic point of view, an age- and sex-matched control group should be used to define a GH threshold. Twit Text FOAVip A Systematic Review of Glomerular Hyperfiltration Assessment and Definition in the Medical Literature ????Clin J Am Soc Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=25568216 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25568216 #FOAvip English Wikipedia <ref>{{Cite pmid|25568216}}</ref> A Systematic Review of Glomerular Hyperfiltration Assessment and Definition in the Medical Literature #MMPMID25568216 Cachat F; Combescure C; Cauderay M; Girardin E; Chehade H Clin J Am Soc Nephrol 2015[Mar]; 10 (3): 382-9 PMID25568216show ga Background and objectives: Evaluation of glomerular hyperfiltration (GH) is difficult; the variable reported definitions impede comparisons between studies. A clear and universal definition of GH would help in comparing results of trials aimed at reducing GH. This study assessed how GH is measured and defined in the literature. Design, setting, participants, & measurements: Three databases (Embase, MEDLINE, CINAHL) were systematically searched using the terms ?hyperfiltration? or ?glomerular hyperfiltration?. All studies reporting a GH threshold or studying the effect of a high GFR in a continuous manner against another outcome of interest were included. Results: The literature search was performed from November 2012 to February 2013 and updated in August 2014. From 2013 retrieved studies, 405 studies were included. Threshold use to define GH was reported in 55.6% of studies. Of these, 88.4% used a single threshold and 11.6% used numerous thresholds adapted to participant sex or age. In 29.8% of the studies, the choice of a GH threshold was not based on a control group or literature references. After 2004, the use of GH threshold use increased (P<0.001), but the use of a control group to precisely define that GH threshold decreased significantly (P<0.001); the threshold did not differ among pediatric, adult, or mixed-age studies. The GH threshold ranged from 90.7 to 175 ml/min per 1.73 m2 (median, 135 ml/min per 1.73 m2). Conclusion: Thirty percent of studies did not justify the choice of threshold values. The decrease of GFR in the elderly was rarely considered in defining GH. From a methodologic point of view, an age- and sex-matched control group should be used to define a GH threshold. äA Systematic Review of Glomerular Hyperfiltration Assessment and Defin(epmc).pdf DeepDyve Pubget Overpricing