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10.1038/jcbfm.2014.223 http://scihub22266oqcxt.onion/10.1038/jcbfm.2014.223 C4348391!4348391!25492119     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25492119&cmd=llinks): Failed to open stream: HTTP request failed! 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Hydrogen sulfide inhalation decreases early blood?brain barrier permeability and brain edema induced by cardiac arrest and resuscitation |pdf=|usr=}}{{25492119}} gab.com Text Hydrogen sulfide inhalation decreases early blood brain barrier permeability and brain edema induced by cardiac arrest and resuscitation JO: J Cereb Blood Flow Metab http://www.kidney.de/pget.php?&tw=1&pmid=25492119 #FOAvip The effects of hydrogen sulfide (H2S) on blood?brain barrier (BBB) and brain edema after cardiac arrest (CA) and cardiopulmonary resuscitation (CPR) remain poorly understood. We investigated the effects of exogenous 80-p.p.m. H2S gas on BBB, brain water content, neurologic outcome, and survival rate after CA and CPR. Cardiopulmonary resuscitation followed CA induced in rats by ventricular fibrillation for 6?minutes. Results show that inhalation of 80-p.p.m. H2S significantly reduced the permeability of the BBB in both in the cortex and hippocampus at 24?hours after resuscitation. Hydrogen sulfide also lessened brain edema in the cortex and hippocampus, ameliorated neurologic outcome as evaluated by neurologic deficit score and tape removal test, and improved the 14-day survival rate. Hydrogen sulfide also attenuated CA and CPR-induced increases of matrix metalloproteinase-9 (MMP-9) activity and vascular endothelial growth factor (VEGF) expression, and increased the expression of angiogenin-1 (Ang-1). These results indicate that inhalation of 80-p.p.m. H2S immediately after CPR attenuated BBB permeability and brain edema, and improved neurologic outcome and 14-day survival of rats after CA. The therapeutic benefits of H2S could be associated with suppression of MMP-9 and VEGF expression and increased expression of Ang-1. Twit Text FOAVip Hydrogen sulfide inhalation decreases early blood brain barrier permeability and brain edema induced by cardiac arrest and resuscitation ????J Cereb Blood Flow Metab http://www.kidney.de/pget.php?&tw=1&pmid=25492119 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25492119 #FOAvip English Wikipedia <ref>{{Cite pmid|25492119}}</ref> Hydrogen sulfide inhalation decreases early blood?brain barrier permeability and brain edema induced by cardiac arrest and resuscitation #MMPMID25492119 Geng Y; Li E; Mu Q; Zhang Y; Wei X; Li H; Cheng L; Zhang B J Cereb Blood Flow Metab 2015[Mar]; 35 (3): 494-500 PMID25492119show ga The effects of hydrogen sulfide (H2S) on blood?brain barrier (BBB) and brain edema after cardiac arrest (CA) and cardiopulmonary resuscitation (CPR) remain poorly understood. We investigated the effects of exogenous 80-p.p.m. H2S gas on BBB, brain water content, neurologic outcome, and survival rate after CA and CPR. Cardiopulmonary resuscitation followed CA induced in rats by ventricular fibrillation for 6?minutes. Results show that inhalation of 80-p.p.m. H2S significantly reduced the permeability of the BBB in both in the cortex and hippocampus at 24?hours after resuscitation. Hydrogen sulfide also lessened brain edema in the cortex and hippocampus, ameliorated neurologic outcome as evaluated by neurologic deficit score and tape removal test, and improved the 14-day survival rate. Hydrogen sulfide also attenuated CA and CPR-induced increases of matrix metalloproteinase-9 (MMP-9) activity and vascular endothelial growth factor (VEGF) expression, and increased the expression of angiogenin-1 (Ang-1). These results indicate that inhalation of 80-p.p.m. H2S immediately after CPR attenuated BBB permeability and brain edema, and improved neurologic outcome and 14-day survival of rats after CA. The therapeutic benefits of H2S could be associated with suppression of MMP-9 and VEGF expression and increased expression of Ang-1. äHydrogen sulfide inhalation decreases early blood?brain barrier permea(epmc).pdf DeepDyve Pubget Overpricing