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10.1146/annurev-micro-091313-103409 http://scihub22266oqcxt.onion/10.1146/annurev-micro-091313-103409 C4348004!4348004!25002095     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Annu+Rev+Microbiol 2014 ; 68 (ä): 477-92 Nephropedia Template TP {{tp|p=25002095|t=2014. Cellular Sensing of Viral DNA and Viral Evasion Mechanisms |pdf=|usr=}}{{25002095}} gab.com Text Cellular Sensing of Viral DNA and Viral Evasion Mechanisms JO: Annu Rev Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=25002095 #FOAvip Mammalian cells detect foreign DNA introduced as free DNA or as a result of microbial infection, leading to the induction of innate immune responses that block microbial replication and the activation of mechanisms that epigenetically silence the genes encoded by the foreign DNA. A number of DNA sensors localized to a variety of sites within the cell have been identified, and this review focuses on the mechanisms that detect viral DNA and how the resulting responses affect viral infections. Viruses have evolved mechanisms that inhibit these host sensors and signaling pathways, and the study of these antagonistic viral strategies has provided insight into the mechanisms of these host responses. The field of cellular sensing of foreign DNA is in its infancy, but our currently limited knowledge has raised a number of important questions for study. Twit Text FOAVip Cellular Sensing of Viral DNA and Viral Evasion Mechanisms ????Annu Rev Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=25002095 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25002095 #FOAvip English Wikipedia <ref>{{Cite pmid|25002095}}</ref> Cellular Sensing of Viral DNA and Viral Evasion Mechanisms #MMPMID25002095 Orzalli MH; Knipe DM Annu Rev Microbiol 2014[]; 68 (ä): 477-92 PMID25002095show ga Mammalian cells detect foreign DNA introduced as free DNA or as a result of microbial infection, leading to the induction of innate immune responses that block microbial replication and the activation of mechanisms that epigenetically silence the genes encoded by the foreign DNA. A number of DNA sensors localized to a variety of sites within the cell have been identified, and this review focuses on the mechanisms that detect viral DNA and how the resulting responses affect viral infections. Viruses have evolved mechanisms that inhibit these host sensors and signaling pathways, and the study of these antagonistic viral strategies has provided insight into the mechanisms of these host responses. The field of cellular sensing of foreign DNA is in its infancy, but our currently limited knowledge has raised a number of important questions for study. äCellular Sensing of Viral DNA and Viral Evasion Mechanisms (epmc).pdf DeepDyve Pubget Overpricing