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10.3390/ijms16022942

http://scihub22266oqcxt.onion/10.3390/ijms16022942
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C4346874!4346874!25636036
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suck abstract from ncbi

pmid25636036      Int+J+Mol+Sci 2015 ; 16 (2): 2942-55
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  • A Time to Kill: Targeting Apoptosis in Cancer #MMPMID25636036
  • Koff JL; Ramachandiran S; Bernal-Mizrachi L
  • Int J Mol Sci 2015[Feb]; 16 (2): 2942-55 PMID25636036show ga
  • The process of apoptosis is essential for maintaining the physiologic balance between cell death and cell growth. This complex process is executed by two major pathways that participate in activating an executioner mechanism leading to chromatin disintegration and nuclear fragmentation. Dysregulation of these pathways often contributes to cancer development and resistance to cancer therapy. Here, we review the most recent discoveries in apoptosis regulation and possible mechanisms for resensitizing tumor cells to therapy.
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