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10.3390/ijms16022269 http://scihub22266oqcxt.onion/10.3390/ijms16022269 C4346836!4346836!25622248     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Mol+Sci 2015 ; 16 (2): 2269-93 Nephropedia Template TP {{tp|p=25622248|t=2015. Unzippers, Resolvers and Sensors: A Structural and Functional Biochemistry Tale of RNA Helicases |pdf=|usr=}}{{25622248}} gab.com Text Unzippers, Resolvers and Sensors: A Structural and Functional Biochemistry Tale of RNA Helicases JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=25622248 #FOAvip The centrality of RNA within the biological world is an irrefutable fact that currently attracts increasing attention from the scientific community. The panoply of functional RNAs requires the existence of specific biological caretakers, RNA helicases, devoted to maintain the proper folding of those molecules, resolving unstable structures. However, evolution has taken advantage of the specific position and characteristics of RNA helicases to develop new functions for these proteins, which are at the interface of the basic processes for transference of information from DNA to proteins. RNA helicases are involved in many biologically relevant processes, not only as RNA chaperones, but also as signal transducers, scaffolds of molecular complexes, and regulatory elements. Structural biology studies during the last decade, founded in X-ray crystallography, have characterized in detail several RNA-helicases. This comprehensive review summarizes the structural knowledge accumulated in the last two decades within this family of proteins, with special emphasis on the structure-function relationships of the most widely-studied families of RNA helicases: the DEAD-box, RIG-I-like and viral NS3 classes. Twit Text FOAVip Unzippers, Resolvers and Sensors: A Structural and Functional Biochemistry Tale of RNA Helicases ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=25622248 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25622248 #FOAvip English Wikipedia <ref>{{Cite pmid|25622248}}</ref> Unzippers, Resolvers and Sensors: A Structural and Functional Biochemistry Tale of RNA Helicases #MMPMID25622248 Leitão AL; Costa MC; Enguita FJ Int J Mol Sci 2015[Feb]; 16 (2): 2269-93 PMID25622248show ga The centrality of RNA within the biological world is an irrefutable fact that currently attracts increasing attention from the scientific community. The panoply of functional RNAs requires the existence of specific biological caretakers, RNA helicases, devoted to maintain the proper folding of those molecules, resolving unstable structures. However, evolution has taken advantage of the specific position and characteristics of RNA helicases to develop new functions for these proteins, which are at the interface of the basic processes for transference of information from DNA to proteins. RNA helicases are involved in many biologically relevant processes, not only as RNA chaperones, but also as signal transducers, scaffolds of molecular complexes, and regulatory elements. Structural biology studies during the last decade, founded in X-ray crystallography, have characterized in detail several RNA-helicases. This comprehensive review summarizes the structural knowledge accumulated in the last two decades within this family of proteins, with special emphasis on the structure-function relationships of the most widely-studied families of RNA helicases: the DEAD-box, RIG-I-like and viral NS3 classes. äUnzippers, Resolvers and Sensors: A Structural and Functional Biochemi(epmc).pdf DeepDyve Pubget Overpricing