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10.1152/ajprenal.00593.2014 http://scihub22266oqcxt.onion/10.1152/ajprenal.00593.2014 C4346745!4346745!25537745     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Physiol+Renal+Physiol 2015 ; 308 (5): F411-9 Nephropedia Template TP {{tp|p=25537745|t=2015. Effect of prenatal programming and postnatal rearing on glomerular filtration rate in adult rats |pdf=|usr=}}{{25537745}} gab.com Text Effect of prenatal programming and postnatal rearing on glomerular filtration rate in adult rats JO: Am J Physiol Renal Physiol http://www.kidney.de/pget.php?&tw=1&pmid=25537745 #FOAvip The present study examined whether a prenatal low-protein diet programs a decrease in glomerular filtration rate (GFR) and an increase in systolic blood pressure (BP). In addition, we examined whether altering the postnatal nutritional environment of nursing neonatal rats affected GFR and BP when rats were studied as adults. Pregnant rats were fed a normal (20%) protein diet or a low-protein diet (6%) during the last half of pregnancy until birth, when rats were fed a 20% protein diet. Mature adult rats from the prenatal low-protein group had systolic hypertension and a GFR of 0.38 ± 0.03 versus 0.57 ± 0.05 ml·min?1·100 g body wt?1 in the 20% group (P < 0.01). In cross-fostering experiments, mothers continued on the same prenatal diet until weaning. Prenatal 6% protein rats cross-fostered to a 20% mother on day 1 of life had a GFR of 0.53 ± 0.05 ml·min?1·100 g body wt?1, which was not different than the 20% group cross-fostered to a different 20% mother (0.45 ± 0.04 ml·min?1·100 g body wt?1). BP in the 6% to 20% group was comparable with the 20% to 20% group. Offspring of rats fed either 20% or 6% protein diets during pregnancy and cross-fostered to a 6% mother had elevated BP but a comparable GFR normalized to body weight as the 20% to 20% control group. Thus, a prenatal low-protein diet causes hypertension and a reduction in GFR in mature adult offspring, which can be modified by postnatal rearing. Twit Text FOAVip Effect of prenatal programming and postnatal rearing on glomerular filtration rate in adult rats ????Am J Physiol Renal Physiol http://www.kidney.de/pget.php?&tw=1&pmid=25537745 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25537745 #FOAvip English Wikipedia <ref>{{Cite pmid|25537745}}</ref> Effect of prenatal programming and postnatal rearing on glomerular filtration rate in adult rats #MMPMID25537745 Lozano G; Elmaghrabi A; Salley J; Siddique K; Gattineni J; Baum M Am J Physiol Renal Physiol 2015[Mar]; 308 (5): F411-9 PMID25537745show ga The present study examined whether a prenatal low-protein diet programs a decrease in glomerular filtration rate (GFR) and an increase in systolic blood pressure (BP). In addition, we examined whether altering the postnatal nutritional environment of nursing neonatal rats affected GFR and BP when rats were studied as adults. Pregnant rats were fed a normal (20%) protein diet or a low-protein diet (6%) during the last half of pregnancy until birth, when rats were fed a 20% protein diet. Mature adult rats from the prenatal low-protein group had systolic hypertension and a GFR of 0.38 ± 0.03 versus 0.57 ± 0.05 ml·min?1·100 g body wt?1 in the 20% group (P < 0.01). In cross-fostering experiments, mothers continued on the same prenatal diet until weaning. Prenatal 6% protein rats cross-fostered to a 20% mother on day 1 of life had a GFR of 0.53 ± 0.05 ml·min?1·100 g body wt?1, which was not different than the 20% group cross-fostered to a different 20% mother (0.45 ± 0.04 ml·min?1·100 g body wt?1). BP in the 6% to 20% group was comparable with the 20% to 20% group. Offspring of rats fed either 20% or 6% protein diets during pregnancy and cross-fostered to a 6% mother had elevated BP but a comparable GFR normalized to body weight as the 20% to 20% control group. Thus, a prenatal low-protein diet causes hypertension and a reduction in GFR in mature adult offspring, which can be modified by postnatal rearing. äEffect of prenatal programming and postnatal rearing on glomerular fil(epmc).pdf DeepDyve Pubget Overpricing