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10.1016/j.tcb.2014.11.004 http://scihub22266oqcxt.onion/10.1016/j.tcb.2014.11.004 C4344861!4344861!25484347     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Trends+Cell+Biol 2015 ; 25 (3): 137-47 Nephropedia Template TP {{tp|p=25484347|t=2015. The biological functions of miRNAs: lessons from in vivo studies |pdf=|usr=}}{{25484347}} gab.com Text The biological functions of miRNAs: lessons from in vivo studies JO: Trends Cell Biol http://www.kidney.de/pget.php?&tw=1&pmid=25484347 #FOAvip Despite their clear importance as a class of regulatory molecules, pinpointing the relevance of individual miRNAs has been challenging. Studies querying miRNA functions by overexpressing or silencing specific miRNAs have yielded data that are often at odds with those collected from loss-of-functions models. In addition, knockout studies suggest that many conserved miRNAs are dispensable for animal development or viability. In this review we discuss these observations in the context of our current knowledge of miRNA biology and review the evidence implicating miRNA-mediated gene regulation in the mechanisms that ensure biological robustness. Twit Text FOAVip The biological functions of miRNAs: lessons from in vivo studies ????Trends Cell Biol http://www.kidney.de/pget.php?&tw=1&pmid=25484347 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25484347 #FOAvip English Wikipedia <ref>{{Cite pmid|25484347}}</ref> The biological functions of miRNAs: lessons from in vivo studies #MMPMID25484347 Vidigal JA; Ventura A Trends Cell Biol 2015[Mar]; 25 (3): 137-47 PMID25484347show ga Despite their clear importance as a class of regulatory molecules, pinpointing the relevance of individual miRNAs has been challenging. Studies querying miRNA functions by overexpressing or silencing specific miRNAs have yielded data that are often at odds with those collected from loss-of-functions models. In addition, knockout studies suggest that many conserved miRNAs are dispensable for animal development or viability. In this review we discuss these observations in the context of our current knowledge of miRNA biology and review the evidence implicating miRNA-mediated gene regulation in the mechanisms that ensure biological robustness. äThe biological functions of miRNAs: lessons from in vivo studies (epmc).pdf DeepDyve Pubget Overpricing