Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1161/STROKEAHA.114.008290 http://scihub22266oqcxt.onion/10.1161/STROKEAHA.114.008290 C4342284!4342284!25604250     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Stroke 2015 ; 46 (3): 874-6 Nephropedia Template TP {{tp|p=25604250|t=2015. To Treat or Not to Treat? A Pilot Survey for Minor and Rapidly Improving Stroke |pdf=|usr=}}{{25604250}} gab.com Text To Treat or Not to Treat A Pilot Survey for Minor and Rapidly Improving Stroke JO: Stroke http://www.kidney.de/pget.php?&tw=1&pmid=25604250 #FOAvip Background and Purpose: Minor stroke and rapidly improving stroke symptoms (RISS) are frequent exclusions for intravenous tissue-type plasminogen activator (t-PA). We explored factors influencing t-PA treatment decision for minor stroke/RISS. Methods: A pilot survey including 110 case scenarios completed by 17 clinicians from two academic medical centers. Respondents were asked whether they would treat each case with t-PA at 60 min after Emergency Department admission. Cases varied by: (a) NIHSS score at treatment decision time; (b) symptom pattern over time [?improvement (IMP)? or ?worsening and then improving (WI)?]; (c) type of neurological deficit [three main domains, ?Motor (M)?, ?Visual/Sensory/Ataxia (VSA)?, ?Language/Neglect (LN)?]; and, (d) age/occupation (four profiles). Logistic regression was used to predict probability of omission (po). A binomial regression model was used to predict probability of treatment decision [p(t-PA)]. Results: P(t-PA) was affected by NIHSS score (p<0.001), age/occupation profiles (p<0.001), but not by symptom patterns (p=0.334). There were significant, albeit modest main effects on p(t-PA) for neurological domains. Responses were most likely omitted (p=0.027) for cases with ?IMP? pattern and ?LN? domain (po)=0.74; 95% [confidence interval (CI) 0.52-0.89] and with ?VSA? domain (po=0.74; CI 0.37-0.93), as compared to ?IMP? pattern and ?M? domain (po =0.17; CI 0.06-0.42) and to any ?WI? patterns (0.37<po<0.56). Conclusions: This pilot survey provides the first quantitative evidence that NIHSS score is not the only determinant of treatment decision. An NIHSS score of 2 is the potential equipoise point, with the least consensus on treatment decision. These preliminary findings require validation in larger population surveys. Twit Text FOAVip To Treat or Not to Treat A Pilot Survey for Minor and Rapidly Improving Stroke ????Stroke http://www.kidney.de/pget.php?&tw=1&pmid=25604250 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25604250 #FOAvip English Wikipedia <ref>{{Cite pmid|25604250}}</ref> To Treat or Not to Treat? A Pilot Survey for Minor and Rapidly Improving Stroke #MMPMID25604250 Balucani C; Bianchi R; Feldmann E; Weedon J; Kolychev D; Levine SR Stroke 2015[Mar]; 46 (3): 874-6 PMID25604250show ga Background and Purpose: Minor stroke and rapidly improving stroke symptoms (RISS) are frequent exclusions for intravenous tissue-type plasminogen activator (t-PA). We explored factors influencing t-PA treatment decision for minor stroke/RISS. Methods: A pilot survey including 110 case scenarios completed by 17 clinicians from two academic medical centers. Respondents were asked whether they would treat each case with t-PA at 60 min after Emergency Department admission. Cases varied by: (a) NIHSS score at treatment decision time; (b) symptom pattern over time [?improvement (IMP)? or ?worsening and then improving (WI)?]; (c) type of neurological deficit [three main domains, ?Motor (M)?, ?Visual/Sensory/Ataxia (VSA)?, ?Language/Neglect (LN)?]; and, (d) age/occupation (four profiles). Logistic regression was used to predict probability of omission (po). A binomial regression model was used to predict probability of treatment decision [p(t-PA)]. Results: P(t-PA) was affected by NIHSS score (p<0.001), age/occupation profiles (p<0.001), but not by symptom patterns (p=0.334). There were significant, albeit modest main effects on p(t-PA) for neurological domains. Responses were most likely omitted (p=0.027) for cases with ?IMP? pattern and ?LN? domain (po)=0.74; 95% [confidence interval (CI) 0.52-0.89] and with ?VSA? domain (po=0.74; CI 0.37-0.93), as compared to ?IMP? pattern and ?M? domain (po =0.17; CI 0.06-0.42) and to any ?WI? patterns (0.37 äTo Treat or Not to Treat? A Pilot Survey for Minor and Rapidly Improvi(epmc).pdf DeepDyve Pubget Overpricing