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10.1016/j.tibs.2015.01.004 http://scihub22266oqcxt.onion/10.1016/j.tibs.2015.01.004 C4340757!4340757!25639751     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Trends+Biochem+Sci 2015 ; 40 (3): 130-40 Nephropedia Template TP {{tp|p=25639751|t=2015. Famine versus feast: understanding the metabolism of tumors in vivo |pdf=|usr=}}{{25639751}} gab.com Text Famine versus feast: understanding the metabolism of tumors in vivo JO: Trends Biochem Sci http://www.kidney.de/pget.php?&tw=1&pmid=25639751 #FOAvip To fuel unregulated proliferation, cancer cells alter metabolism to support macromolecule biosynthesis. Cell culture studies have revealed how different oncogenic mutations and nutrients impact metabolism. Glucose and glutamine are the primary fuels used in vitro; however, recent studies have suggested that utilization of other amino acids as well as lipids and protein can also be important to cancer cells. Early investigations of tumor metabolism are translating these findings to the biology of whole tumors and suggest that additional complexity exists beyond nutrient availability alone in vivo. Whole body metabolism and tumor heterogeneity also influence the metabolism of tumor cells, and successful targeting of metabolism for cancer therapy will require an understanding of tumor metabolism in vivo. Twit Text FOAVip Famine versus feast: understanding the metabolism of tumors in vivo ????Trends Biochem Sci http://www.kidney.de/pget.php?&tw=1&pmid=25639751 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25639751 #FOAvip English Wikipedia <ref>{{Cite pmid|25639751}}</ref> Famine versus feast: understanding the metabolism of tumors in vivo #MMPMID25639751 Mayers JR; Vander Heiden MG Trends Biochem Sci 2015[Mar]; 40 (3): 130-40 PMID25639751show ga To fuel unregulated proliferation, cancer cells alter metabolism to support macromolecule biosynthesis. Cell culture studies have revealed how different oncogenic mutations and nutrients impact metabolism. Glucose and glutamine are the primary fuels used in vitro; however, recent studies have suggested that utilization of other amino acids as well as lipids and protein can also be important to cancer cells. Early investigations of tumor metabolism are translating these findings to the biology of whole tumors and suggest that additional complexity exists beyond nutrient availability alone in vivo. Whole body metabolism and tumor heterogeneity also influence the metabolism of tumor cells, and successful targeting of metabolism for cancer therapy will require an understanding of tumor metabolism in vivo. äFamine versus feast: understanding the metabolism of tumors in vivo (epmc).pdf DeepDyve Pubget Overpricing