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10.1016/j.tibs.2015.01.003 http://scihub22266oqcxt.onion/10.1016/j.tibs.2015.01.003 C4340748!4340748!25636997     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Trends+Biochem+Sci 2015 ; 40 (3): 157-64 Nephropedia Template TP {{tp|p=25636997|t=2015. Probing RNA?protein networks: biochemistry meets genomics |pdf=|usr=}}{{25636997}} gab.com Text Probing RNA protein networks: biochemistry meets genomics JO: Trends Biochem Sci http://www.kidney.de/pget.php?&tw=1&pmid=25636997 #FOAvip RNA?protein interactions are pervasive. The specificity of these interactions dictates which RNAs are controlled by what protein. Here we describe a class of revolutionary new methods that enable global views of RNA-binding specificity in vitro, for both single proteins and multiprotein complexes. In vitro methods provide insight into central issues in RNA regulation in living cells, including understanding the balance between free and bound components in cells, the basis for exclusion of binding sites in vivo, detection of binding events in the absence of discernible regulatory elements, and new approaches to targeting specific cellular RNAs by design. Comparisons of in vitro and in vivo binding provide a foundation for comprehensive understanding of the biochemistry of protein-mediated RNA regulatory networks. Twit Text FOAVip Probing RNA protein networks: biochemistry meets genomics ????Trends Biochem Sci http://www.kidney.de/pget.php?&tw=1&pmid=25636997 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25636997 #FOAvip English Wikipedia <ref>{{Cite pmid|25636997}}</ref> Probing RNA?protein networks: biochemistry meets genomics #MMPMID25636997 Campbell ZT; Wickens M Trends Biochem Sci 2015[Mar]; 40 (3): 157-64 PMID25636997show ga RNA?protein interactions are pervasive. The specificity of these interactions dictates which RNAs are controlled by what protein. Here we describe a class of revolutionary new methods that enable global views of RNA-binding specificity in vitro, for both single proteins and multiprotein complexes. In vitro methods provide insight into central issues in RNA regulation in living cells, including understanding the balance between free and bound components in cells, the basis for exclusion of binding sites in vivo, detection of binding events in the absence of discernible regulatory elements, and new approaches to targeting specific cellular RNAs by design. Comparisons of in vitro and in vivo binding provide a foundation for comprehensive understanding of the biochemistry of protein-mediated RNA regulatory networks. äProbing RNA?protein networks: biochemistry meets genomics (epmc).pdf DeepDyve Pubget Overpricing